1305196-76-2

Upstream product

• 73548-77-3 Boc-L-Lys(Z)-OMe 
• 1798-06-7 (4-iodophenyl)acetic acid 
• 55757-60-3 N-α-(tert-butoxycarbonyl)-L-lysine methyl ester 
• 2389-45-9 Boc-Lys(Z)-OH 

Downstream Products

• 1305196-77-3 methyl 2-(tert-butoxycarbonylamino)-6-(2-(4-(4-phenyl-2H-1,2,3-triazol-2-yl)phenyl)acetamido)hexanoate 

Relevant academic research and scientific papers

N-2-Aryl-1,2,3-triazoles: A novel class of UV/blue-light-emitting fluorophores with tunable optical properties

The N-2-aryl-1,2,3-triazole derivatives (NATs) were developed as a new class of UV/blue-light-emitting fluorophores. Though both N-1-aryl-1,2,3- triazoles and N-2-aryl-1,2,3-triazoles gave strong photo absorption under excitation at 330 nm, only the N-2-analogous showed strong fluorescence emission in the UV/blue range with high efficiency in various solvents (quantum yield Φ around 0.3-0.5). Significant substituted group effects were observed, allowing tunable optical properties with emission (λmax) from 350-400 nm and Stokes shift from 38-93 nm. The computational studies along with X-ray crystal structures indicated the significance of the effective conjugation between triazole ring and aryl groups on the N-2 position. The planar intramolecular charge transfer (PICT) mechanism was proposed, which was supported by solvent effect studies. Simple derivatizations gave NAT-modified lysine and strong UV/blue emitting bis-NAT (Φ=0.76, λmax= 390), which suggested the great potential of this new class of fluorophores in biological and material science research.