1305334-94-4

Upstream product

• 252932-48-2 3-amino-2-ethoxycarbonylpyrrole 
• 578-57-4 2-bromoanisole 
• 1305334-93-3 ethyl 1'H-1,3'-bipyrrole-2'-carboxylate 
• 529-28-2 4-iodoanisol 

Downstream Products

• 1010732-14-5 [4,5-dichloro-1-[4,5-dichloro-2-(2-hydroxybenzoyl)-1H-pyrrol-3-yl]pyrrol-2-yl]-(2-hydroxyphenyl)methanone 
• 1305334-97-7 (4,4',5,5'-tetrachloro-1'H-1,3'-bipyrrole-2,2'-diyl)bis((2-acetoxyphenyl)methanone) 
• 1227869-60-4 1'H-1,3'-bipyrrole-2,2'-diylbis[(2-hydroxyphenyl)methanone] 
• 1227869-61-5 (4,4′,5,5′-tetrachloro-1′H-[1,3′-bipyrrole]-2,2′-diyl)bis((2-methoxyphenyl)methanone) 
• 1305334-95-5 C₂₄H₁₆Br₄N₂O₄ 
• 1305334-96-6 C₂₂H₁₂Br₄N₂O₄ 
• 1305335-02-7 C₁₉H₁₈N₂O₄ 
• 1305335-03-8 C₁₉H₁₄Cl₄N₂O₄ 
• 1305334-99-9 C₁₈H₁₂Cl₄N₂O₄ 
• 1227869-59-1 1'H-1,3'-bipyrrole-2,2'-diylbis[(2-methoxyphenyl)methanone] 
• 1228555-50-7 (5-chloro-2-hydroxyphenyl)(4,4',5,5'-tetrachloro-2'-(2-hydroxybenzoyl)-1'H-[1,3'-bipyrrol]-2-yl)methanone 

Relevant academic research and scientific papers

MARINOPYRROLE DERIVATIVES AS ANTICANCER AGENTS

Marinopyrrole derivatives and methods for their synthesis and use are described herein. The methods of using the compounds include treating and preventing cancer.

MCL-1 MODULATING COMPOSITIONS

The present invention relates to marinopyrrole A derivatives and pyoluteorin derivatives and methods of treatment of disorders associated with misregulation of Mcl-l, e.g., leukemia, lymphoma, multiple myeloma, melanoma, or pancreatic cancer. We describe exemplary compounds, which may be contained in pharmaceutical compositions, and their use as therapeutic agents either alone or in combination with other anti-cancer treatments, e.g., anti-Bcl- 2 agents.

Marinopyrrole derivatives as potential antibiotic agents against methicillin-resistant Staphylococcus aureus (I)

Infections caused by drug-resistant pathogens are on the rise. The ongoing spread of methicillin-resistant Staphylococcus aureus (MRSA) strains exemplifies the urgent need for new antibiotics. The marine natural product, marinopyrrole A, was previously sh

Total synthesis and biological evaluation of marinopyrrole A and analogs

A five-step total synthesis of the antibiotic marinopyrrole A (1) is described. The developed synthetic technology enabled the synthesis of several marinopyrrole A analogs whose antibacterial properties against methicillin-resistant Staphylococcus aureus TCH1516 were evaluated.