130534-91-7

Upstream product

• 109-87-5 Dimethoxymethane 
• 873-75-6 4-bromobenzenemethanol 
• 107-30-2 chloromethyl methyl ether 

Downstream Products

• 130534-92-8 2,2,2-Trifluoro-1-(4-methoxymethoxymethyl-phenyl)-ethanone 
• 454678-92-3 4-[(methoxymethyloxy)methyl]-phenylboric acid 
• 16532-79-9 4-Bromophenylacetonitrile 
• 55883-45-9 4-bromobenzyliodide 
• 589-15-1 1-bromomethyl-4-bromobenzene 
• 454678-93-4 2-{4-[(methoxymethyloxy)methyl]phenyl}thiazole 
• 454678-91-2 (4-(thiazol-2-yl)phenyl)methanol 
• 1392440-51-5 C₁₄H₁₆O₂S 
• 86605-93-8 (4-bromobenzyloxy)trimethylsilane 
• 21388-92-1 4-bromobenzyl acetate 
• 873-75-6 4-bromobenzenemethanol 
• 130534-93-9 2,2,2-Trifluoro-1-(4-methoxymethoxymethyl-phenyl)-ethanol 
• 130534-93-9 2,2,2-Trifluoro-1-(4-methoxymethoxymethyl-phenyl)-ethanol 
• 130534-97-3 (+)-p-<(1-hydroxy-2,2,2-trifluoro)ethyl>benzoic acid 

Relevant academic research and scientific papers

Metal hydrogen sulfates catalyzed methoxymethylation of alcohols under solvent-free conditions

Methoxymethylation of a variety of alcohols was performed by using formaldehyde dimethoxy acetal in the presence of metal hydrogen sulfate M(HSO4)n at room temperature and solvent-free conditions. The methoxymethyl ethers (MOM-ethers

Molybdatophosphoric acid as a catalyst for the methoxymethylation of alcohols under solvent-free conditions

The methoxymethylation of alcohols was performed using formaldehyde dimethoxy acetal in the presence of H3PMo12O 40·xH2O at room temperature under solvent-free conditions.

BiCl3-Facilitated removal of methoxymethyl-ether/ester derivatives and DFT study of -O-C-O- bond cleavage

A simple method for the cleavage of methoxymethyl (MOM)-ether and ester derivatives using bismuth trichloride (BiCl3) is described. The alkyl, alkenyl, alkynyl, benzyl and anthracene MOM ether derivatives, as well as MOM esters of both aliphatic and aromatic carboxylic acids, were deprotected in good yields. To better understand the molecular roles of BiCl3and water for MOM cleavage, two possible binding pathways were investigated using the density functional theory (DFT) method. The theoretical results indicate the differential initial binding site preferences of phenolic and alcoholic MOM substrates to the Bi atom and suggest that water plays a key role in facilitating the cleavage of the MOM group.

Methoxymethylation of substituted alcohols using dimethoxymethane over Mo(VI)/ZrO2

The methoxymethylation reaction of alcohols was studied on Mo/ZrO2 (MZ) catalysts. The catalyst containing 5, 10 and 15 % Mo(VI) ions was prepared by solution combustion method. These solid acid catalytic materials were characterized by NH3- TPD, powder XRD, BET, FTIR spectroscopy, scanning electron microscopy, transmission electron spectroscopy and ICP- OES techniques. These catalysts were evaluated for their catalytic activity in the synthesis of methoxymethylation reactions of various substituted alcohols with dimethoxymethane in shorter reaction times (20 min) at moderate temperature (40 °C) with excellent yields (around 99 %). The main features of the Mo/ZrO2 catalyzed reaction are high yields, ease of scale up to gram scale, recyclable catalysts, inexpensive reagents, ecofriendly catalysts and a solvent free approach for the synthesis of methoxymethylated products.

H3PW12O40at the[bmim][FeCl4]: A green catalytic system for alkoxymethylation of alcohols and their one-pot interconversion to acetates and TMS-ethers

12-Tungstophosphoric acid immobilized on [bmim][FeCl4] was found to be an efficient catalyst for chemoselective methoxymethylation and ethxoymethylation of alcohols and also one-pot conversion of MOM- or EOM-ethers to their corresponding acetates and TMS-ethers under thermal conditions and microwave irradiation. These procedures were simple, rapid and the corresponding products were obtained in high yields. The catalyst exhibited remarkable reactivity and was reusable.

[InCl4]: An efficient catalyst-medium for alkoxymethylation of alcohols and their interconversion to acetates and TMS-ethers

A simple, green and chemoselective method for methoxymethylation and ethoxymethylation of primary and secondary alcohols using a Lewis acidic room temperature ionic liquid, [C4mim][InCl4], as catalyst and reaction medium under ambient temperature, microwave and ultrasonic irradiations is reported. In this catalytic system, the corresponding MOM-and EOM-ethers are obtained in excellent yields and in short reaction times. Furthermore, this catalytic system was used for mild and efficient transformations of these protected alcohols to their corresponding acetates and trimethylsilyl ethers under thermal conditions and microwave and ultrasonic irradiations.

Highly efficient and selective methoxymethylation of alcohols and phenols catalyzed by high-valent tin(IV) porphyrin

An efficient and selective method for methoxymethylation of alcohols and phenols with formaldehyde dimethyl acetal (FDMA) catalyzed by electron deficient tin(IV)tetraphenylporphyrinato trifluoromethanesulfonate, [SnIV(TPP)(OTf)2], is

Highly efficient and selective methoxymethylation of alcohols and phenols catalyzed by reusable ZrO(OTf)2 under solvent-free conditions

Different primary, secondary, and tertiary alcohols were efficiently converted to their corresponding methoxymethyl ethers with formaldehyde dimethyl acetal in the presence of catalytic amounts of ZrO(OTf)2 at room temperature. Phenols were als

A mild and efficient method for the methoxymethylation and acetylation of alcohols promoted by benzyltriphenylphosphonium tribromide

A mild and efficient method for the conversion of alcohols to their corresponding methoxymethyl ethers and acetates using benzyltriphenylphosphonium tribromide (BTPTB) as catalyst is described. All reactions were performed under completely heterogeneous reaction conditions in good to high yields.

N,N,N′,N′-tetrabromobenzene-1,3-disulfonamide and poly(N-bromo-N-ethyl-benzene-1,3-disulfonamide) as efficient catalysts for the methoxymethylation of alcohols under solvent-free conditions

Methoxymethylation of a variety of alcohols was performed using formaldehyde dimethyl acetal in the presence of N,N,N′,N′- tetrabromobenzene-1,3-disulfonamide [TBBDA] and poly(N-bromo-N-ethyl-benzene-1, 3-disulfonamide) [PBBS] as catalysts at room tempera