130537-05-2Relevant academic research and scientific papers
Fluoro-Julia olefination as a mild, high-yielding route to α-fluoro acrylonitriles
Del Solar, Maria,Ghosh, Arun K.,Zajc, Barbara
experimental part, p. 8206 - 8211 (2009/04/11)
(Chemical Equation Presented) Synthesis of a novel, stable reagent (1,3-benzothiazol-2-ylsulfonyl)fluoroacetonitrile from readily synthesized ethyl α-(1,3-benzothiazol-2-ylsulfanyl)-α-fluoroacetate is reported. Aldehydes undergo condensations with (1,3-be
Synthesis and Diels-Alder reactions of α-fluoro- and α-trifluoromethylacrylonitriles
Nenajdenko, Valentine G.,Muzalevskiy, Vasiliy M.,Shastin, Aleksey V.,Balenkova, Elizabeth S.,Haufe, Günter
, p. 818 - 826 (2008/03/14)
A novel synthetic method for the preparation of α-fluoro- and the still unknown α-trifluoromethylacrylonitriles is elaborated. The reaction of α-fluorovinylbromides and α-trifluoromethylvinylbromides with CuCN leads to the title compounds in good to high yields. While the α-fluoroacrylonitriles were isolated as mixture of Z/E-isomers, the α-trifluoromethylacrylonitriles were obtained as pure Z-isomers. The α-trifluoromethylacrylonitriles are shown to be excellent dienophiles for Diels-Alder reactions.
Preparation of Fluoralkenes from Fluoroacetonitrile
Patrick, Timothy B.,Nadji, Sourena
, p. 147 - 150 (2007/10/02)
A fluorocyanophosphate prepared from fluoroacetonitrile at low temperature reacts with aromatic aldehydes in a modified Wittig procedure to give fluorocyanoalkenes in moderate yield.
