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Usage

Uses

Used in Pharmaceutical Applications:
1(2H)-Phthalazinone, 4-(phenylmethyl)-, hydrazone is used as a potential drug candidate for the treatment of various diseases and conditions due to its unique chemical structure and properties. Its hydrazone nature and phenylmethyl substituent may offer specific advantages in targeting and treating certain health issues, making it a valuable compound for further exploration in the field of medicinal chemistry.
Used in Medicinal Chemistry Research:
In the realm of medicinal chemistry, 1(2H)-Phthalazinone, 4-(phenylmethyl)-, hydrazone serves as a subject of interest for researchers. Its unique properties and potential applications in drug development make it a promising candidate for further study, with the aim of understanding its full potential and optimizing its use in the treatment of various diseases and conditions.
Used in Drug Discovery:
1(2H)-Phthalazinone, 4-(phenylmethyl)-, hydrazone's potential pharmaceutical applications also make it a valuable asset in drug discovery. Researchers can use 1(2H)-Phthalazinone, 4-(phenylmethyl)-, hydrazone as a starting point for developing new drugs or improving existing ones, potentially leading to more effective treatments for a range of health issues.

Upstream product

• 103-82-2 phenylacetic acid 
• 85-44-9 phthalic anhydride 
• 32003-14-8 4-benzyl-2H-phthalazin-1-one 
• 59908-32-6 4-benzylphthalazine-1(2H)-thione 
• 40848-53-1 1-benzyl-4-chlorophthalazine 

Downstream Products

• 134513-62-5 Ethyl pyruvate (4-benzylphthalazin-1-yl)hydrazone 
• 135085-39-1 6-benzyl-s-triazolo<3,4-a>phthalazin-3-thione 
• 134513-67-0 7-benzyl-4-oxo-3-phenyl-1,2,4-triazino<3,4-a>phthalazine 
• 135085-30-2 N-Formyl-N'(4-benzylphthalazin-1-yl)hydrazine 
• 130538-69-1 6-benzyl-3-(D-gluco-1,2,3,4,5-pentaacetoxypentyl)-1,2,4-triazolo<3,4-a>phthalazine 
• 135085-37-9 6-Benzyl-3-(3,5-dimethoxyphenyl)-s-triazolo<3,4-a>phthalazine 
• 134513-56-7 6-Benzyl-1,2,4-triazolo<3,4-a>phthalazine 
• 135085-31-3 N-Acetyl-N'(4-benzylphthalazin-1-yl)hydrazine 
• 134513-70-5 6-benzyl-3-methyl-1,2,4-triazolo<3,4-a>phthalazine 
• 134513-71-6 ethyl acetoacetate (4-benzylphthalazin-1-yl)hydrazone 
• 130538-68-0 6-benzyl-3-(D-glycero-D-gulo-hexahydroxyhexyl)-1,2,4-triazolo<3,4-a>phthalazine 
• 135085-33-5 6-Benzyl-3-phenyl-s-triazolo<3,4-a>phthalazine 
• 135085-35-7 6-Benzyl-3-(4-hydroxyphenyl)-s-triazolo<3,4-a>phthalazine 
• 135085-36-8 6-Benzyl-3-(4-methoxyphenyl)-s-triazolo<3,4-a>phthalazine 

Relevant academic research and scientific papers

Design and synthesis of new phthalazinone derivatives containing benzyl moiety with anticipated antitumor activity

The acetohydrazide derivative reacted with carbon electrophiles such as acid chlorides, acetylacetone, ethyl acetoacetate and aromatic aldehydes to give some interesting heterocyclic compounds. The hydrazide derivative reacted with acetophenone which in turn underwent Vielsmeier-Haack reaction. Also, the phthalazinethione has been synthesized and its behavior towards hydrazine hydrate, oxidizing agent and ethyl chloroacetate has been investigated. The newly synthesized compounds were characterized by spectroscopic data. The antimicrobial, the cytotoxic, and the antioxidant activities of some of the synthesized products were evaluated. Some of the tested compounds showed very strong cytotoxic activity with respect to the standard.

CYCLOCONDENSATION OF 1-HYDRAZINO-4-BENZYLPHTHALAZINE

The synthesis of s-triazolophthalazines 5-7 and 10, 11 from 1-hydrazino-4-benzylphthalazine 1 was achieved.Moreover, application of Mannich conditions to compounds 10 and 11 afforded the corresponding Mannich bases 14 and 15.The new products were c

Cyclocondensation of 4-Benzyl-1-hydrazinophthalazine

1-Hydrazino-4-benzylphthalazine 1 underwent closure and/or condensation reaction with formic acid, acetic acid, acetic anhydride, trifluoroacetic anhydride, ortho esters, aldehydes, urea or carbon disulphide to afford the N-formyl 3a, N-acyl 3b, and the a