130540-28-2

Upstream product

• 130540-29-3 [(S)-6-Benzyloxycarbonylamino-2-({8-[((S)-6-benzyloxycarbonylamino-2-tert-butoxycarbonylamino-hexanoylamino)-methyl]-naphthalene-2-carbonyl}-amino)-hexanoylamino]-acetic acid 
• 130540-27-1 [(S)-2-({8-[((S)-2-Amino-6-benzyloxycarbonylamino-hexanoylamino)-methyl]-naphthalene-2-carbonyl}-amino)-6-benzyloxycarbonylamino-hexanoylamino]-acetic acid methyl ester; hydrochloride 

Downstream Products

• 152768-75-7 Cyclo<-Amn-Lys(Z)-Gly-Lys(Z)-Amn-Lys(Z)-Gly-Lys(Z)-> 

Relevant academic research and scientific papers

Template-Assembled Synthetic Proteins (TASP). Cyclic Templates with Incorporated Turn-Inducing Mimics

The 8-amino-5,6,7,8-tetrahydronaphth-2-oic acid (1), 8-(aminomethyl)-5,6,7,8-tetrahydronaphth-2-oic acid (2), and 8-(aminomethyl)naphth-2-oic acid (3) were synthesized in their protected forms as turn-inducing dipeptide mimics.Two of them (2 and 3) were i

SYNTHESIS OF A 4-HELIX BUNDLE-LIKE TEMPLATE-ASSEMBLED SYNTHETIC PROTEIN (TASP) BY CONDENSATION OF A PROTECTED PEPTIDE ON A CONFORMATIONALLY CONSTRAINED CYCLIC CARRIER

We describe the condensation in solution of a fully protected helix model peptide to a cyclic peptide template including a new turn-inducing mimic to obtain a 4-helix bundle protein-like TASP.This approach allows the total synthesis of chemically and structurally well-defined protein models in the 6-10 kDa range.