130540-29-3Relevant academic research and scientific papers
SYNTHESIS OF A 4-HELIX BUNDLE-LIKE TEMPLATE-ASSEMBLED SYNTHETIC PROTEIN (TASP) BY CONDENSATION OF A PROTECTED PEPTIDE ON A CONFORMATIONALLY CONSTRAINED CYCLIC CARRIER
Ernest, I.,Vuilleumier, S.,Fritz, H.,Mutter, M.
, p. 4015 - 4018 (2007/10/02)
We describe the condensation in solution of a fully protected helix model peptide to a cyclic peptide template including a new turn-inducing mimic to obtain a 4-helix bundle protein-like TASP.This approach allows the total synthesis of chemically and structurally well-defined protein models in the 6-10 kDa range.
