13055-49-7

Upstream product

• 146388-50-3 (3S,4R)-3,4-epoxy-4-phenylbutan-2-one 
• 103-79-7 1-phenyl-acetone 
• 109-94-4 formic acid ethyl ester 

Downstream Products

• 103-79-7 1-phenyl-acetone 
• 77831-67-5 (E)-4-Diphenylamino-3-phenyl-but-3-en-2-one 
• 5948-49-2 1-Chlor-2-phenyl-but-1-en-3-on 
• 77831-80-2 3-Chloro-4-diethylamino-6-methyl-5-phenyl-pyran-2-one 
• 77831-74-4 Diethyl-(6-methyl-2,2-dioxo-5-phenyl-3,4-dihydro-2H-2λ⁶-[1,2]oxathiin-4-yl)-amine 
• 77831-81-3 3-Chloro-6-methyl-4-(methyl-phenyl-amino)-5-phenyl-pyran-2-one 
• 77831-75-5 1-(6-Methyl-2,2-dioxo-5-phenyl-3,4-dihydro-2H-2λ⁶-[1,2]oxathiin-4-yl)-piperidine 
• 77831-77-7 3,3-Dichloro-6-methyl-4-(methyl-phenyl-amino)-5-phenyl-3,4-dihydro-pyran-2-one 
• 77831-76-6 4-(6-Methyl-2,2-dioxo-5-phenyl-3,4-dihydro-2H-2λ⁶-[1,2]oxathiin-4-yl)-morpholine 
• 77831-82-4 3-Chloro-4-diphenylamino-6-methyl-5-phenyl-pyran-2-one 
• 77831-78-8 3,3-Dichloro-4-diphenylamino-6-methyl-5-phenyl-3,4-dihydro-pyran-2-one 
• 77831-66-4 (E)-4-(Methyl-phenyl-amino)-3-phenyl-but-3-en-2-one 
• 128340-59-0 (E)-4-Morpholin-4-yl-3-phenyl-but-3-en-2-one 

Relevant academic research and scientific papers

AuCl3/AgSbF6-catalyzed rapid epoxide to carbonyl rearrangement

An efficient epoxide to carbonyl rearrangement using catalytic AuCl 3/AgSbF6 has been presented. The reactions are fast and high yielding. β-Hydrogen migration takes place exclusively when hydrogen and methyl or substituted methyl groups are present at β-carbon of epoxide. When phenyl/acetyl/benzoyl and hydrogen are available at same carbon atom, migration of the former is preferred over the latter.

Reaction of Sulfene and Dichloroketene with Open-Chain N,N-Disubstituted α-Aminomethyleneketones. Synthesis of 4-Dialkylamino-3,4-dihydro-6-methyl-5-phenyl-1,2-oxathiin 2,2-Dioxides and of N,N-Disubstituted 4-Amino-3-chloro-(6-methyl-5-phenyl)(6-benzyl)-2H-pyran-2-ones

Cycloaddition of sulfene to N,N-disubstituted 4-amino-3-phenyl-3-buten-2-ones (III) occurred in good yield only in the case of aliphatic N-substitution to give 4-dialkylamino-3,4-dihydro-6-methyl-5-phenyl-1,2-oxathiin 2,2-dioxides, whereas N,N-disubstituted 4-amino-1-phenyl-3-buten-2-ones (IV) did not react at all.Polar 1,4-cycloaddition of dichloroketene to III and IV occurred partly in the case of aromatic N-substitution, with the exception of the morpholino derivative IVd, giving in low yield N,N-disubstituted 4-amino-3,3-dichloro-3,4-dihydro-(6-methyl-5-phenyl)(6-benzyl)-2H-pyran-2-ones, which were dehydrochlorinated with DBN to the corresponding 4-amino-3-chloro-(6-methyl-5-phenyl)(6-benzyl)-2H-pyran-2-ones (VII) in good yield.In some cases of aliphatic N,N-disubstitution of III and IV, cycloaddition led directly to N,N-dialkyl derivatives VII in low yield.