130573-32-9Relevant academic research and scientific papers
A Cardioselective, Hydrophilic N,N,N-Trimethylethanaminium α-Tocopherol Analogue That Reduces Myocardial Infarct Size
Grisar, J. Martin,Petty, Margaret A.,Bolkenius, Frank N.,Dow, James,Wagner, Joseph,et al.
, p. 257 - 260 (1991)
The α-tocopherol analogue 3,4-dihydro-6-hydroxy-N,N,N,2,5,7,8-heptamethyl-2H-1-benzopyran-2-ethanaminium 4-methylbenzenesulfonate (1a, MDL 73404) and its O-acetate 1b (MDL 74270) were synthesized.Compound 1a was found to be hydrophilic (log P = -0.60) and
Cardioprotective tocopherol analogs
-
, (2008/06/13)
This invention relates to quaternary ammonium salts of certain 2H-1-benzopyran derivatives, to the intermediates and processes useful for their preparation, to their free-radical scavenger and cellular protective properties and to their end-use application as therapeutic agents.
