A Cardioselective, Hydrophilic N,N,N-Trimethylethanaminium α-Tocopherol Analogue That Reduces Myocardial Infarct Size

DOI: 10.1021/jm00105a040

Source and publish data:

Journal of Medicinal Chemistry p. 257 - 260 (1991)

Update date:2022-08-05

Topics:

Authors:

Grisar, J. Martin

Petty, Margaret A.

Bolkenius, Frank N.

Dow, James

Wagner, Joseph

et al. et al.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00105a040

The α-tocopherol analogue 3,4-dihydro-6-hydroxy-N,N,N,2,5,7,8-heptamethyl-2H-1-benzopyran-2-ethanaminium 4-methylbenzenesulfonate (1a, MDL 73404) and its O-acetate 1b (MDL 74270) were synthesized.Compound 1a was found to be hydrophilic (log P = -0.60) and

Full text of DOI:10.1021/jm00105a040

Products guided by the article

Product name:2-(6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydro-2H-chromen-2-yl)-N,N,N-trimethylethanaminium 4-methylbenzenesulfonate

Cas No:130573-32-9

R&D Labs maybe for 130573-32-9

Changzhou Sunsheng Chem Co., Ltd

Contact:+1-(989)-854-0648

Address:No. 28 Yinshan Rd., Xixiashu Industrial Park
HANGZHOU ZHONGCHANG SCIENTIFIC CO.,LTD

Contact:+86-571-88932183

Address:Hangzhou
Purestar Chem Enterprise Co.,Ltd

website:http://www.purestarchem.com

Contact:05722157374

Address:no235.huanchengdong Rd
HANGZHOU FOREWIN PHARMA CO., LTD

Contact:+86-571-89053961

Address:hangzhou
TIANJIN GST CHEMICAL TECHNOLOGY CO., LTD

Contact:+86-22-25210964

Address:Room. 208, No. -12-C, No. 13, Xinbei Road, Tanggu District, New Haixin Area, Tianjin City, China

Relevant to this article

Reaction of Methyl (E)-2-Phenyl-1-azirine-3-acrylates with Hydrazines and Amidines. Synthetic and Mechanistic Implications

Doi:10.1021/jo00001a004
(1991)
Diastereoselective Addition of Organometallics to Chiral α-Keto Amides Having trans-2,5-Disubstituted Pyrrolidine

Doi:10.1246/cl.1990.1749
(1990)
Asymmetric organocatalytic reduction of ketimines with catecholborane employing a N-triflyl phosphoramide Br?nsted acid as catalyst

Doi:10.1016/j.tetlet.2012.11.055
(2013)
Concise synthesis of bicyclic aminals by way of catalytic intramolecular C-H amination and evaluation of their reactivity as iminium precursors

Doi:10.2174/157017811795038340
(2011)
Discovery of the selective and efficacious inhibitors of FLT3 mutations

Doi:10.1016/j.ejmech.2018.06.010
(2018)
Synthesis of β-Hydroxysulfones from Sulfonyl Chlorides and Alkenes Utilizing Visible Light Photocatalytic Sequences

Doi:10.1021/acs.orglett.6b00734
(2016)

Article Doi