130611-34-6

Upstream product

• 73252-54-7 (2-bromo-3,4,5-trimethoxyphenyl)methanol 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 41879-37-2 t-butyldimethylsilyl amine 
• 69739-34-0 t-butyldimethylsiyl triflate 

Downstream Products

• 130611-39-1 (4S,5S)-2-[6'-(tert-Butyl-dimethyl-silanyloxymethyl)-4,5,6,2',3',4'-hexamethoxy-biphenyl-2-yl]-4-methoxymethyl-5-phenyl-4,5-dihydro-oxazole 
• 130611-39-1 (4S,5S)-2-[6'-(tert-Butyl-dimethyl-silanyloxymethyl)-4,5,6,2',3',4'-hexamethoxy-biphenyl-2-yl]-4-methoxymethyl-5-phenyl-4,5-dihydro-oxazole 
• 130611-55-1 (4R,5R)-2-{2-[6'-(tert-Butyl-dimethyl-silanyloxymethyl)-4,5,6,2',3',4'-hexamethoxy-biphenyl-2-yl]-1-methyl-ethyl}-4-methoxymethyl-5-phenyl-4,5-dihydro-oxazole 
• 130611-45-9 6'-Acetoxymethyl-4,5,6,2',3',4'-hexamethoxy-biphenyl-2-carboxylic acid (1S,2S)-2-acetylamino-3-methoxy-1-phenyl-propyl ester 
• 130611-45-9 6'-Acetoxymethyl-4,5,6,2',3',4'-hexamethoxy-biphenyl-2-carboxylic acid (1S,2S)-2-acetylamino-3-methoxy-1-phenyl-propyl ester 
• 130611-44-8 4,5,6,2',3',4'-Hexamethoxy-6'-methyl-biphenyl-2-carboxylic acid ((R)-1-methoxymethyl-2-phenyl-ethyl)-amide 
• 130611-44-8 4,5,6,2',3',4'-Hexamethoxy-6'-methyl-biphenyl-2-carboxylic acid ((R)-1-methoxymethyl-2-phenyl-ethyl)-amide 
• 130611-43-7 6'-Hydroxymethyl-4,5,6,2',3',4'-hexamethoxy-biphenyl-2-carboxylic acid ((R)-1-methoxymethyl-2-phenyl-ethyl)-amide 
• 130611-43-7 6'-Hydroxymethyl-4,5,6,2',3',4'-hexamethoxy-biphenyl-2-carboxylic acid ((R)-1-methoxymethyl-2-phenyl-ethyl)-amide 
• 130611-42-6 [4,5,6,2',3',4'-Hexamethoxy-6'-((4S,5S)-4-methoxymethyl-5-phenyl-4,5-dihydro-oxazol-2-yl)-biphenyl-2-yl]-methanol 
• 130611-42-6 [4,5,6,2',3',4'-Hexamethoxy-6'-((4S,5S)-4-methoxymethyl-5-phenyl-4,5-dihydro-oxazol-2-yl)-biphenyl-2-yl]-methanol 
• 130611-37-9 (4S,5S)-2-(4,5,6,2',3',4'-Hexamethoxy-6'-methoxymethyl-biphenyl-2-yl)-4-methoxymethyl-5-phenyl-4,5-dihydro-oxazole 

Relevant academic research and scientific papers

Tert-Butyldimethylsilyl Amine (TBDMS-NH2): A Mild and Green Reagent for the Protection of Benzyl Alcohols, Phenols, and Carboxylic Acids under Solvent-Free Conditions

Herein, we present the use of the tert-butyldimethylsilyl amine (TBDMS-NH2) as a silylating reagent for phenols, benzyl alcohols, and carboxylic acids. Unlike other silyl protection reactions, this reported process with TBDMS-NH2 does not involve the form

Diversity oriented microwave-assisted synthesis of (-)-steganacin aza-analogues

(Chemical Equation Presented) A novel microwave-assisted, highly efficient protocol for the synthesis of hitherto unknown aza-analogues of (-)-Steganacin, a naturally occurring bisbenzocyclooctadiene lignan lactone with potent antileukemic and tubulin polymerization inhibitory activity, has been developed. Focused microwave irradiation is demonstrated to be highly beneficial in promoting the three crucial steps of the sequence to effect the final ring closure: the Suzuki-Miyaura reaction, Cu-mediated A3-coupling, as well as the intramolecular Huisgen 1,3-dipolar cycloaddition.