130652-10-7

Upstream product

• 874-42-0 2,4-dichlorobenzaldeyhde 
• 149-73-5 trimethyl orthoformate 
• 67-56-1 methanol 

Downstream Products

• 130652-15-2 meso-1,2-bis-(2',4'-dichlorophenyl)-1,2-dimethoxyethane 
• 130652-15-2 d,l-1,2-bis-(2',4'-dichlorophenyl)-1,2-dimethoxyethane 

Relevant academic research and scientific papers

A simple, one-pot oxidative esterification of aryl aldehydes through dialkyl acetal using hydrogen peroxide

A simple and an efficient one-pot procedure has been developed to synthesize various aryl carboxylic esters directly from aryl aldehydes using hydrogen peroxide without any catalyst. The reaction proceeds smoothly at room temperature. A preliminary investigation suggests the formation of dialkyl acetal as an intermediate during the reaction sequence.

NEMATICIDAL N-(2-SUBSTITUTED 2-PHENYLETHYL)CARBOXAMIDES AND N-(2-SUBSTITUTED 2-PHENYLETHYL)-THIOCARBOXAMIDES

The present invention relates to the use of known and novel N-(2- substituted 2-phenylethyl)carboxamides and N-(2-substituted 2-phenylethyl)thiocarboxamides, for the control of plant damaging nematodes in agriculture and further relates to novel N-(2- substituted 2-phenylethyl)carboxamides and N-(2-substituted 2-phenylethyl)thiocarboxamides, processes and intermediate compounds for their preparation, their use as nematicides and their use as anthelmintics against endoparasites in animals and humans, compositions containing such compounds and methods for the control of nematodes and helminths.

Efficient enantioselective synthesis of dihydropyrans using a chiral N, N ′-dioxide as organocatalyst

The bifunctional organocatalyst C3 N,N′-dioxide has been successfully applied to the asymmetric cascade Michael/hemiacetalization reaction of α-substituted cyano ketones and β,γ-unsaturated α-ketoesters for the synthesis of multifunctionalized chiral dihydropyrans. The corresponding products were obtained in excellent yields (up to 99%) with high to excellent enantioselectivities (up to 99% ee).

Carbophilic reactions of amines or methanol with thioaldehyde-S-oxides

Correspondence and reprints Reaction of primary aliphatic amines with 7-ethylenic thioaldehyde-S-oxides la,b affords the corresponding imines 2a,b via a carbophilic addition of amine. When treated with sodium methoxide (1 equiv) and an excess of a primary amine, some methyl sulfinates 3 or 6, bearing a benzylic or allylic chain on the sulfur, are converted into imines 4 or 7. Treatment of the methyl sulfinates 3 with methoxide anion in THF or methanol generally affords a mixture of aldehydes 9, the corresponding dimethylacetals 14, a,a'-dimethoxydisulfides 10, esters 11, thionoesters 12 and methyl a-methoxysulfinates 15, whose ratios depend on the conditions. The formation of these compounds is best explained by a deprotonationelimination of the methyl sulfinates into the corresponding thioaldehyde-S-oxides; which then undergo a carbophilic addition of methoxide anion or methanol. Several possible reaction paths from the so-formed a-methoxysulfenate anions IX are discussed for their conversion into the final compounds. unsaturated sulfinic ester / elimination / thioaldehyde-S-oxide / imine / aldehyde / a,a -dimethoxydisulflde / thionoester / methyl u-methoxysulflnate Eisevier,.