1306597-69-2Relevant academic research and scientific papers
Poly(ADP-Ribose) - A unique natural polymer structural features, biological role and approaches to the chemical synthesis
Drenichev, Mikhail S.,Mikhailov, Sergey N.
, p. 258 - 276 (2015/03/30)
Poly(ADP-ribose) (PAR) is a natural polymer, taking part in numerous important cellular processes. Several enzymes are involved in biosynthesis and degradation of PAR. One of them, poly(ADP-ribose)polymerase-1 (PARP-1) is considered to be a perspective ta
Ribosylation of adenosine: An orthogonally protected building block for the synthesis of ADP-ribosyl oligomers
Van Der Heden Van Noort, Gerbrand J.,Overkleeft, Herman S.,Van Der Marel, Gijsbert A.,Filippov, Dmitri V.
, p. 2920 - 2923 (2011/08/02)
A method to ribosylate adenosine on the 2 hydroxyl function in an α-selective fashion and in good yield is presented. Protective groups chosen for the acceptor and donor used in this glycosylation not only direct α-selectivity but also allow the construct
