1306739-43-4 Usage
General Description
Tert-butyl (9-benzyl-1-oxa-9-azaspiro[5.5]undec-4-yl)carbamate is a unique chemical compound that contains a tert-butyl group, a benzyl group, and a carbamate group. The spiro ring structure with an oxygen and nitrogen atom creates a spirocyclic compound with potential pharmaceutical applications. The presence of the tert-butyl and benzyl groups add bulk and steric hindrance, which may impact the compound's reactivity and stability. Overall, tert-butyl (9-benzyl-1-oxa-9-azaspiro[5.5]undec-4-yl)carbamate has interesting structural properties that warrant further exploration in the field of medicinal chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 1306739-43-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,0,6,7,3 and 9 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1306739-43:
(9*1)+(8*3)+(7*0)+(6*6)+(5*7)+(4*3)+(3*9)+(2*4)+(1*3)=154
154 % 10 = 4
So 1306739-43-4 is a valid CAS Registry Number.
1306739-43-4Relevant articles and documents
Attachment of a 5-nitrofuroyl moiety to spirocyclic piperidines produces non-toxic nitrofurans that are efficacious in vitro against multidrug-resistant Mycobacterium tuberculosis
Krasavin, Mikhail,Lukin, Alexei,Vedekhina, Tatiana,Manicheva, Olga,Dogonadze, Marine,Vinogradova, Tatiana,Zabolotnykh, Natalia,Rogacheva, Elizaveta,Kraeva, Liudmila,Sharoyko, Vladimir,Tennikova, Tatiana B.,Dar'in, Dmitry,Sokolovich, Evgeny
, p. 125 - 135 (2019)
A selectively antimycobacterial compound belonging to the nitrofuran class of antimicrobials has been developed via conjugation of the nitrofuran moiety to a series of spirocyclic piperidines through an amide linkage. It proved to have comparable activity against drug-sensitive (H37Rv) strain as well as multidrug-resistant, patient-derived strains of Mycobacterium tuberculosis. The compound is druglike, showed no appreciable cytotoxicity toward human retinal pigment epithelial cell line ARPE-19 in concentrations up to 100 μM and displayed low toxicity when evaluated in mice.
