114342-11-9Relevant articles and documents
Studies on the Biosynthesis of Clavulanic Acid. Part 4. Synthetic Routes to the Monocyclic β-Lactam Precursor, Proclavaminic Acid
Baggaley, Keith H.,Elson, Stephen W.,Nicholson, Neville H.,Sime, John T.
, p. 1513 - 1520 (2007/10/02)
Aldol condensation of 3-substituted propionaldehydes with the lithium enolate of ethyl or benzyl(2-oxoazetidin-1-yl)acetate yielded derivatives of proclavaminic acid.The proportion of the threo diastereoisomer in the aldol product could be increased by th