Welcome to LookChem.com Sign In|Join Free

CAS

  • or

1306763-24-5

Post Buying Request

1306763-24-5 Suppliers

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

1306763-24-5 Usage

Description

(1R)-1-hydroxy-2,3-dihydro-1H-indene-4-carbonitrile is a chemical compound with the molecular formula C10H9NO. It is a derivative of indene, a bicyclic aromatic hydrocarbon, and features a hydroxy group and a carbonitrile group. The (1R) designation signifies the stereochemistry of the molecule, with the hydroxy group positioned on the first carbon of the indene ring. This unique structure and the presence of functional groups make it a candidate for organic synthesis and pharmaceutical development.

Uses

Used in Pharmaceutical Development:
(1R)-1-hydroxy-2,3-dihydro-1H-indene-4-carbonitrile is used as a building block in the synthesis of pharmaceuticals due to its unique structure and functional groups. The hydroxy and carbonitrile groups can be utilized in various chemical reactions to create new compounds with potential medicinal properties.
Used in Organic Synthesis:
In the field of organic synthesis, (1R)-1-hydroxy-2,3-dihydro-1H-indene-4-carbonitrile serves as a reagent or intermediate in the preparation of complex organic molecules. Its functional groups can be selectively modified to produce a range of chemical products, making it a versatile component in organic chemistry.
Used in Research and Development:
(1R)-1-hydroxy-2,3-dihydro-1H-indene-4-carbonitrile is also used in research and development settings to study the effects of stereochemistry on chemical reactions and to explore new synthetic pathways. Its unique structure provides opportunities for scientists to investigate novel reactions and mechanisms, contributing to the advancement of organic chemistry and pharmaceutical science.

Check Digit Verification of cas no

The CAS Registry Mumber 1306763-24-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,0,6,7,6 and 3 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1306763-24:
(9*1)+(8*3)+(7*0)+(6*6)+(5*7)+(4*6)+(3*3)+(2*2)+(1*4)=145
145 % 10 = 5
So 1306763-24-5 is a valid CAS Registry Number.

1306763-24-5Relevant articles and documents

Enantioselective Synthesis of Ozanimod, the Active Pharmaceutical Ingredient of a New Drug for Multiple Sclerosis

Cianferotti, Claudio,Barreca, Giuseppe,Bollabathini, Venkatesh,Carcone, Luca,Grainger, Damian,Staniland, Samantha,Taddei, Maurizio

, p. 1924 - 1930 (2021/04/05)

We report here a short enantioselective synthesis of Ozanimod, a potent modulator of the enzyme Sphingosine-1-phosphate receptor (S1PR), recently approved by FDA and EMA for the treatment of relapsing-remitting multiple sclerosis. Amongst different synthetic approaches explored, we achieved the best result introducing the stereogenic centre in the last step through imine asymmetric transfer hydrogenation (ATH) using Wills’ catalysts. Besides the reduced numbers of enantiomeric purity controls required, this process culminates in an exceptionally high enantioselective reductive amination obtained with commercially available tethered Ru catalysts. Starting from commercially available 4-cyano-indanone, enantiomerically pure Ozanimod was obtained in 5 steps in 62 % overall yield and 99 % ee.

Method for preparing (S)-1-amino-2,3-dihydro-1H-indene-4-carbonitrile

-

Paragraph 0020; 0023; 0024, (2019/10/04)

The invention discloses a method for preparing (S)-1-amino-2,3-dihydro-1H-indene-4-carbonitrile. The method comprises the following steps: 1, adding 4-cyano-1-indanone to tetrahydrofuran, adding (S)-2-methyl-CBS-oxazaborolidine, cooling the obtained solut

HETERCYCLIC COMPOUNDS FOR THE TREATMENT OF DISEASE

-

, (2018/12/13)

Described herein are heterocyclic compounds, compositions, and methods for their use for treatment of disease.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 1306763-24-5