130715-80-9

Basic information

• Product Name: 4-[4-(3-Hydroxy-propyl)-piperazin-1-yl]-6-(4-methoxy-phenyl)-2-oxo-2H-pyran-3-carbonitrile
• CAS NO: 130715-80-9
• Molecular Weight: 369.42
• Mol File: 130715-80-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-[4-(3-Hydroxy-propyl)-piperazin-1-yl]-6-(4-methoxy-phenyl)-2-oxo-2H-pyran-3-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[4-(3-Hydroxy-propyl)-piperazin-1-yl]-6-(4-methoxy-phenyl)-2-oxo-2H-pyran-3-carbonitrile(130715-80-9)
• EPA Substance Registry System: 4-[4-(3-Hydroxy-propyl)-piperazin-1-yl]-6-(4-methoxy-phenyl)-2-oxo-2H-pyran-3-carbonitrile(130715-80-9)

Safety Data

• Hazardous Substances Data: 130715-80-9(Hazardous Substances Data)

Upstream product

• 100-06-1 1-(4-methoxyphenyl)ethanone 
• 5317-32-8 3-(1-piperazinyl)-1-propanol 
• 61380-86-7 6-(4-methoxyphenyl)-3-cyano-4-methylsulfanyl-2H-pyran-2-one 

Relevant articles and documents

Synthesis and reactions of 6-aryl-3-cyano-4-methylthio-2H-pyran-2-ones

Reaction of different acetyl compounds with ethyl β, β-bis(methylthio)-α-cyanoacrylate in the presence of powdered potassium hydroxide yields 6-aryl-3-cyano-4-methylthio-2H-pyran-2-ones (1a,b) which react readily with various nucleophiles such as amine, reactive methylene compounds to provide substituted products (2-19) in good yields.