130719-76-5Relevant academic research and scientific papers
Characterization of orally active nonpeptide vasopressin V2 receptor agonist. Synthesis and biological evaluation of both the (5R)- and (5S)-enantioisomers of 2-[1-(2-chloro-4-pyrrolidin-1-yl-benzoyl)- 2,3,4,5-tetrahydro-1H-1-benzazepin-5-yl]-N
Kondo, Kazumi,Kan, Keizo,Tanada, Yoshihisa,Bando, Masahiko,Shinohara, Tomoichi,Kurimura, Muneaki,Ogawa, Hidenori,Nakamura, Shigeki,Hirano, Takahiro,Yamamura, Yoshitaka,Kido, Masaru,Mori, Toyoki,Tominaga, Michiaki
, p. 3805 - 3808 (2007/10/03)
The synthesis and evaluation of both the (R)- and (S)-enantioisomers about the 5-position on a tetrahydro-1H-1-benzazepine derivative were described. The absolute configuration of the (R,R)-isomer (10) was determined by x-ray crystallographic analysis. Af
Distorted amides as models for activated peptide N-C=O units. 2. The synthesis, hydrolytic profile, and molecular structure of 3,4-dihydro-2-oxo-1,4-propanoquinoline
Wang, Qingping,Bennet, A. J.,Brown, R. S.,Santarsiero, B. D.
, p. 1732 - 1739 (2007/10/02)
A distorted anilide (3,4-dihydro-2-oxo-1,4-propanoquinoline (3)) has been synthesized, its structure determined by X-ray diffraction, and its hydrolysis profile from pH 0-13 investigated.The amide unit in 3 is distorted in that the N lone pair is twisted
