192513-61-4

Upstream product

• 911312-93-1 2-chloro-4-pyrrolidin-1-ylbenzoyl chloride 
• 192513-58-9 methyl 2,3,4,5-tetrahydro-1H-1-benzazepin-5-ylacetate 
• 24310-36-9 1-tosyl-2,3,4,5-tetrahydro-1H-1-benzazepin-5-one 
• 192513-60-3 2-chloro-(4-pyrrolidin-1-yl) benzoic acid 
• 130719-76-5 ethyl {1-[(4-methylphenyl)sulfonyl]-1,2,3,4-tetrahydro-5H-1-benzazepin-5-ylidene}acetate 
• 872-50-4 1-methyl-pyrrolidin-2-one 

Downstream Products

• 192513-62-5 [1-(2-chloro-4-pyrrolidin-1-ylbenzoyl)-2,3,4,5-tetrahydro-1H-1-benzazepin-5-yl] acetic acid 
• 192513-65-8 (1R)-1-methylhexyl (5R)-[1-(2-chloro-4-pyrrolidin-1-ylbenzoyl)-2,3,4,5-tetrahydro-1H-1-benzazepin-5-yl]acetate 
• 192514-54-8 OPC 51803 
• 192514-55-9 (5R)-[1-(2-chloro-4-pyrrolidin-1-ylbenzoyl)-2,3,4,5-tetrahydro-1H-1-benzazepin-5-yl]acetic acid 

Relevant academic research and scientific papers

Characterization of orally active nonpeptide vasopressin V2 receptor agonist. Synthesis and biological evaluation of both the (5R)- and (5S)-enantioisomers of 2-[1-(2-chloro-4-pyrrolidin-1-yl-benzoyl)- 2,3,4,5-tetrahydro-1H-1-benzazepin-5-yl]-N

The synthesis and evaluation of both the (R)- and (S)-enantioisomers about the 5-position on a tetrahydro-1H-1-benzazepine derivative were described. The absolute configuration of the (R,R)-isomer (10) was determined by x-ray crystallographic analysis. Af

Benzazepine derivatives with vasopressin agonistic activity

PCT No. PCT/JP96/03652 Sec. 371 Date Jun. 12, 1998 Sec. 102(e) Date Jun. 12, 1998 PCT Filed Dec. 13, 1996 PCT Pub. No. WO97/22591 PCT Pub. Date Jun. 26, 1997Novel benzazepine derivative of the formula [1]: wherein R1 is H or halogen, A is lower alkylene,