1307313-50-3

Basic information

• Product Name: 2'-chloro-1-((1-(2,6-dimethylphenyl)-3-methyl-1H-pyrazol-4-yl)methyl)-4',4'-difluoro-4',5'-dihydrospiro[piperidine-4,7'-thieno[2,3-c]pyran]
• Synonyms: 2'-chloro-1-((1-(2,6-dimethylphenyl)-3-methyl-1H-pyrazol-4-yl)methyl)-4',4'-difluoro-4',5'-dihydrospiro[piperidine-4,7'-thieno[2,3-c]pyran]
• CAS NO: 1307313-50-3
• Molecular Weight: 478.006
• Mol File: 1307313-50-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2'-chloro-1-((1-(2,6-dimethylphenyl)-3-methyl-1H-pyrazol-4-yl)methyl)-4',4'-difluoro-4',5'-dihydrospiro[piperidine-4,7'-thieno[2,3-c]pyran](CAS DataBase Reference)
• NIST Chemistry Reference: 2'-chloro-1-((1-(2,6-dimethylphenyl)-3-methyl-1H-pyrazol-4-yl)methyl)-4',4'-difluoro-4',5'-dihydrospiro[piperidine-4,7'-thieno[2,3-c]pyran](1307313-50-3)
• EPA Substance Registry System: 2'-chloro-1-((1-(2,6-dimethylphenyl)-3-methyl-1H-pyrazol-4-yl)methyl)-4',4'-difluoro-4',5'-dihydrospiro[piperidine-4,7'-thieno[2,3-c]pyran](1307313-50-3)

Safety Data

• Hazardous Substances Data: 1307313-50-3(Hazardous Substances Data)

Upstream product

• 13781-67-4 3-(2-hydroxyethyl)thiophene 
• 1307248-45-8 tert-butyl 2′-chloro-4′,5′-dihydrospiro-[piperidine-4,7′-thieno[2,3-c]pyran]-1-carboxylate 
• 1307248-42-5 2'-chloro-4',5'-dihydrospiro[piperidine-4,7'-thieno[2,3-c]pyran] hydrochloride 
• 1307248-48-1 tert-butyl 2-chloro-4,4-difluoro-4,5-dihydrospiro[5H-thieno[2,3-c]pyran-7,4'-piperidine]-1'-carboxylate 
• 1307248-46-9 tert-butyl-2′-chloro-4′-oxo-4′,5′-dihydrospiro[piperidine-4,7′-thieno[2,3-c]pyran]-1-carboxylate 
• 1307248-44-7 2-chloro-4,4-difluoro-4,5-dihydrospiro[5H-thieno[2,3-c]pyran-7,4'-piperidine] 
• 1307314-46-0 1-(2,6-dimethylphenyl)-3-methyl-1H-pyrazole-4-carbaldehyde 
• 1307248-40-3 4',5'-dihydrospiro[piperidine-4,7'-thieno[2,3-c]pyran]-1-ium trifluoroacetate 
• 1283095-47-5 4′,5′-dihydrospiro[piperidine-4,7′-thieno[2,3-c]pyran] 
• 100379-00-8 2,6-dimethylbenzene boronic acid 
• 112758-40-4 3-methyl-1H-pyrazole-4-carbaldehyde 

Relevant articles and documents

SPIROPIPERIDINE COMPOUNDS AS ORL-1 RECEPTOR ANTAGONISTS

An ORL-1 receptor antagonist of the formula: its uses, and methods for its preparation are described. ORL-1 antagonists are deemed to be useful in the treatment of depression and/or the treatment of overweight, obesity, and/or weight maintenance post treatment for overweight or obesity. Certain compounds have also demonstrated through animal models that the compounds of the present invention are useful for the treatment of migraines.