130778-80-2Relevant academic research and scientific papers
Copper-mediated trifluoromethylation of potassium alkynyltrifluoroborates with Langlois' reagent Dedicated to Professor Pierre Vogel on the occasion of his 70th birthday
Dubbaka, Srinivas Reddy,Nizalapur, Shashidhar,Atthunuri, Azmi Reddy,Salla, Manohar,Mathew, Thresen
, p. 2118 - 2121 (2014/03/21)
Synthesis of trifluoromethylated acetylenes by copper-mediated trifluoromethylation of potassium alkynyltrifluoroborates with CF3 radicals generated from NaSO2CF3 and tert-butyl hydroperoxide (TBHP) is communicated. The trifluoromethylated acetylenes were obtained in good to moderate yields. The presented method tolerates a wide range of aromatic, heteroaromatic, and aliphatic potassium alkynyltrifluoroborates.
Mild copper-catalyzed trifluoromethylation of terminal alkynes using an electrophilic trifluoromethylating reagent
Weng, Zhiqiang,Li, Huaifeng,He, Weiming,Yao, Liang-Feng,Tan, Jianwei,Chen, Jinfa,Yuan, Yaofeng,Huang, Kuo-Wei
supporting information; experimental part, p. 2527 - 2531 (2012/04/23)
A catalytic process for trifluoromethylation of terminal alkynes with Togni's reagent has been developed, affording trifluoromethylated acetylenes in good to excellent yields. The reaction is conducted at room temperature and exhibits tolerance to a range
