1307801-57-5

Basic information

• Product Name: ethyl 1-(2-(3,5-dimethylphenylamino)pyrimidin-4-yl)-3-methyl-1H-pyrazole-4-carboxylate
• Synonyms: ethyl 1-(2-(3,5-dimethylphenylamino)pyrimidin-4-yl)-3-methyl-1H-pyrazole-4-carboxylate
• CAS NO: 1307801-57-5
• Molecular Weight: 351.408
• Mol File: 1307801-57-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: ethyl 1-(2-(3,5-dimethylphenylamino)pyrimidin-4-yl)-3-methyl-1H-pyrazole-4-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 1-(2-(3,5-dimethylphenylamino)pyrimidin-4-yl)-3-methyl-1H-pyrazole-4-carboxylate(1307801-57-5)
• EPA Substance Registry System: ethyl 1-(2-(3,5-dimethylphenylamino)pyrimidin-4-yl)-3-methyl-1H-pyrazole-4-carboxylate(1307801-57-5)

Safety Data

• Hazardous Substances Data: 1307801-57-5(Hazardous Substances Data)

Upstream product

• 1307803-04-8 ethyl 3-methyl-1-(2-(methylthio)pyrimidin-4-yl)-1H-pyrazole-4-carboxylate 
• 85290-78-4 ethyl 3-methylpyrazole-4-carboxylate 
• 1307803-05-9 ethyl 3-methyl-1-(2-(methylsulfonyl)pyrimidin-4-yl)-1H-pyrazole-4-carboxylate 
• 108-69-0 3,5-dimethylaminoaniline 

Downstream Products

• 1307801-58-6 1-(2-(3,5-dimethylphenylamino)pyrimidin-4-yl)-3-methyl-1H-pyrazole-4-carboxylic acid 
• 1307801-83-7 1-(2-(3,5-dimethylphenylamino)pyrimidin-4-yl)-N-(2-hydroxyethyl)-N,3-dimethyl-1H-pyrazole-4-carboxamide 
• 1307801-60-0 (1-(2-(3,5-dimethylphenylamino)pyrimidin-4-yl)-3-methyl-1H-pyrazol-4-yl)methanol 

Relevant articles and documents

Highly potent and selective pyrazolylpyrimidines as Syk kinase inhibitors

A series of pyrazolylpyrimidine scaffold based Syk inhibitors were synthesized and evaluated for their biological activities and selectivity. Lead optimization efforts provided compounds with potent Syk inhibition in both enzymatic and TNF-α release assay.