130796-33-7

Upstream product

• 82082-57-3 2,3-Dihydroxy-3-(4-methoxy-phenyl)-propionitrile 
• 34025-30-4 (S)-Hydroxy-(4-methoxy-phenyl)-acetaldehyde 
• 33646-40-1 (S)-4-methoxymandelonitrile 
• 344256-01-5 5-(4-Methoxy-phenyl)-2,2-dimethyl-[1,3]dioxolane-4-carbonitrile 
• 130852-60-7 3-(4-methoxyphenyl)-1,1-bis(p-tolylthio)-3-(trimethylsilyloxy)propan-2-one 
• 130718-74-0 cis-4--5-(4-methoxyphenyl)-2,2-dimethyl-1,3-dioxolan 
• 130796-22-4 3-hydroxy-3-(4-methoxyphenyl)-1,1-bis(p-tolylthio)propan-2-one 
• 130718-70-6 erythro 3-(4-methoxyphenyl)-1,1-bis(p-tolylthio)propane-2,3-diol 
• 130718-81-9 1,1-bis(ethylthio)-3-(4-methoxyphenyl)-3-(trimethylsilyloxy)propan-2-one 
• 130718-85-3 cis-4--2,2-dimethyl-5-(4-methoxyphenyl)-1,3-dioxolan 
• 130735-54-5 erythro rac-1,1-bis(ethylthio)-3-(4-methoxyphenyl)propane-2,3-diol 
• 130718-84-2 rac-1,1-bis(ethylthio)-3-hydroxy-3-(4methoxyphenyl)propan-2-one 
• 13305-14-1 methyl 2-hydroxy-2-(4-methoxyphenyl)acetate 
• 130796-19-9 methyl 2-(4-methoxyphenyl)-2-(trimethylsilyloxy)acetate 

Downstream Products

• 125073-64-5 (-)-(2R,3R)-methyl-2,3-dihydroxy-3-para-methoxyphenyl-propanoate 
• 106146-94-5 methyl 2,3-dihydroxy-3-(4-methoxyphenyl)propanoate 
• 122431-48-5 methyl cis-5-(4-methoxyphenyl)-2,2-dimethyl-1,3-dioxolan-4-carboxylate 
• 130796-36-0 (4R,5R)-5-(4-Methoxy-phenyl)-2,2-dimethyl-[1,3]dioxolane-4-carboxylic acid (S)-1-methyl-heptyl ester 
• 130796-38-2 methyl (4R,5R)-cis-5-(4-methoxyphenyl)-2,2-dimethyl-1,3-dioxolan-4-carboxylate 

Relevant academic research and scientific papers

Synthesis of Aryl Carbohydrate Synthons and 2,3-Dihydroxypropanoic Acid Derivatives of High Optical Purity

General routes to bith L and D aryl carbohydrate precursors and to erythro and threo 2,3-dihydroxypropanoic acid of high optical purity have been established from readily available optically active aryl cyanohydrins.

SYNTHESIS OF THREO-3-ARYL-2,3-DIHYDROXYPROPANOIC ACID DERIVATIVES WITH HIGH OPTICAL PURITY

Cyanohydrins of arylaldehides can be obtained in high optical purity using the'Inoue' dipeptide catalyst system and converted into enantiomerically and diastereochemically pure threo-3-aryl-2,3-dihydroxypropanoic acid derivatives using a route which involves a novel base-catalysed equilibration of the acetonides of the cyanodiols.