130796-95-1Relevant academic research and scientific papers
Synthesis, reactivity, and bioactivity of avermectin B1-3,4-oxide
Blizzard, Timothy A.,Mrozik, Helmut,Preiser, Franz A.,Fisher, Michael H.
, p. 4965 - 4968 (1990)
Avermectin B1-3,4-oxide (2) has been synthesized from avermectin B1 (1). While epoxide 2 is comparable to avermectin B1 in bioactivity, opening of the epoxide leads to derivatives which are substantially less bioactive.
