130817-40-2

Upstream product

• 106553-84-8 7-oxabicyclo<4.1.0>heptane-2-propanoic acid, 5-oxo, methyl ester,(1.β,2.β,6.β) 
• 106553-84-8 7-oxabicyclo<4.1.0>heptane-2-propanoic acid, 5-oxo, methyl ester,(1.β,2.α,6.β) 
• 106553-86-0 7-oxabicyclo<4.1.0>heptane-2-propanoic acid, 5-tetra-decylidene-, methyl ester,(1.β,2.α,5Z,6.β) 
• 13266-02-9 n-tridecyltriphenylphosphonium bromide 
• 106553-89-3 cyclohexanepropanoic acid, 2-hydroxy-3-<(2-methoxy-2-oxoethyl)thiol>-4-tetradecylidene-, methyl ester,(1.α,2β,3α,4Z) 
• 106553-86-0 7-oxabicyclo<4.1.0>heptane-2-propanoic acid, 5-tetradecylidene-,methyl ester (1.β,2.α,5Z,6.β) 
• 106553-89-3 cyclohexanepropanoic acid, 2-hydroxy-3-<(2-methoxy-2-oxoethyl)thio>-4-tetradecylidene-, methyl ester, (1.β,2.β,3.α,4Z) 

Relevant academic research and scientific papers

CONFORMATIONALLY RESTRICTED LEUKOTRIENE ANTAGONISTS. STEREOSELECTIVE SYNTHESIS OF SOME LEUKOTRIENE D4 ANALOGS

The stereocontrolled synthesis of conformationally restricted LTD4 analogs 2a, b is described.Epoxidation of enone 4 affords a 2.4:1 mixture of trans-epoxide 5 and cis-epoxide 9.Stereocontrolled elaboration of each epoxide to final product invo