CONFORMATIONALLY RESTRICTED LEUKOTRIENE ANTAGONISTS. STEREOSELECTIVE SYNTHESIS OF SOME LEUKOTRIENE D4 ANALOGS

DOI: 10.1016/S0040-4020(01)86751-X

Source and publish data:

Tetrahedron p. 4155 - 4160 (1990)

Update date:2022-08-05

Topics:

Authors:

Sabol, Jeffrey S.

Weintraub, Philip M.

Gieske, Thomas H.

Cregge, Robert J.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4020(01)86751-X

The stereocontrolled synthesis of conformationally restricted LTD₄ analogs 2a, b is described.Epoxidation of enone 4 affords a 2.4:1 mixture of trans-epoxide 5 and cis-epoxide 9.Stereocontrolled elaboration of each epoxide to final product invo

Full text of DOI:10.1016/S0040-4020(01)86751-X

Products guided by the article

Product name:acetic acid,<(octahydro-2-oxo-7-tetradecylidene-2H-1-benzo-pyran-8-yl)thio>-,(4a.α,7Z,8.α,8a.β)

Cas No:130817-40-2

R&D Labs maybe for 130817-40-2

Oren Hydrocarbons (Qingdao) Co., Ltd.

Contact:+86-532-68607667-801

Address:Room 3 # 302, No.9 Qingyun Road, Qingdao, China
Shanghai Sunway Pharmaceutical Technology Co.,Ltd.

Contact:+86-21-5161 3915

Address:Shanghai YangPu
Hawks Chemical

Contact:+44 (0)161 367 9441

Address:
Cangzhou Senary Chemical Science-tech Co., Ltd

Contact:+86-317-3563899, 3563699

Address:168 Jinde Road, Cangzhou, Hebei, China
LINYI FUDE FINE CHEMICAL CO.,LTD

Contact:86-539-2361184

Address:YISHUI, LINYI,SAHNDONG,CHINA

Relevant to this article

Cyclocondensation of 2-lithiomethylthiazoles and 2-lithiomethylthiazoline with α-oxoketene dithioacetals: Synthesis of substituted and annelated thiazolo- and dihydrothiazolo[3,2-a]pyridinium compounds

Doi:10.1016/S0040-4020(01)86767-3
(1990)
A Facile One-Pot Synthesis of 3-Dialkoxyphosphoryl- and 3--1-hydroxyindoles

Doi:10.1055/s-1990-27020
(1990)
Coordination chemistry of the soft chiral Lewis acid [Cp*Ir(TsDPEN)] ⁺

Doi:10.1021/ic200160q
(2011)
TBHP/CoCl₂-mediated intramolecular oxidative cyclization of N-(2-formylphenyl)amides: An approach to the construction of 4H-3,1-benzoxazin-4-ones

Doi:10.1002/ejoc.201501359
(2016)
Application of silver N-heterocyclic carbene complexes in O-glycosidation reactions

Doi:10.1016/j.carres.2011.07.025
(2011)
Intramolecular palladium-catalyzed aminocarboxylation of olefins as a direct route to bicyclic oxazolidinones

Doi:10.1002/adsc.201000889
(2011)

Article Doi