1308299-19-5Relevant articles and documents
The effect of systematic structural modifications on the antibacterial activity of novel oxazolidinones
Pinter, Gabor,Bereczki, Ilona,Roth, Elizabeth,Sipos, Attila,Varghese, Reny,Udo, Edet Ekpenyong,Ostorhazi, Eszter,Rozgonyi, Ferenc,Phillips, Oludotun Adebayo,Herczegh, Pal
experimental part, p. 45 - 55 (2012/01/11)
A novel series of tetraethylene glycol (TEG) triazolyl and squaramide containing oxazolidinones were synthesized and tested for their antibacterial activity against a selected panel of Gram-positive and Gram-negative bacteria. The 4-TEG-triazolyl derivatives were prepared by 'click reaction'. The introduction of the TEG and squaramide groups did not favor antibacterial activity. The three nucleoside-containing oxazolidinones were also prepared by 'click' methodology resulted in weak antibacterial activity.