1308317-29-4Relevant academic research and scientific papers
Synthesis of chiral tetrahydrofurans via catalytic asymmetric [3 + 2] cycloaddition of heterosubstituted alkenes with oxiranes
Yuan, Xiao,Lin, Lili,Chen, Weiliang,Wu, Wangbin,Liu, Xiaohua,Feng, Xiaoming
, p. 1237 - 1243 (2016/02/19)
An efficient diastereo- and enantioselective [3 + 2] cycloaddition of heterosubstituted alkenes with oxiranes via selective C-C bond cleavage of epoxides has been developed. The reaction was catalyzed by a chiral N,N′-dioxide/Ni(II) catalyst, and a variety of chiral highly substituted tetrahydrofurans were obtained in up to 99% yield, 92/8 dr, and 99% ee.
Chiral N,N'-dioxide-scandium(III)-catalyzed asymmetric epoxidation of 2-arylidene-1,3-diketones with hydrogen peroxide
Chu, Yangyang,Hao, Xiaoyu,Lin, Lili,Chen, Weiliang,Li, Wei,Tan, Fei,Liu, Xiaohua,Feng, Xiaoming
supporting information, p. 2214 - 2218 (2014/07/21)
The catalytic asymmetric epoxidation of 2-arylidene-1,3-diketones using aqueous 30% H2O2 as oxidant has been successfully realized by a N,N'-dioxide-scandium(III) triflate [Sc(OTf)3] complex, giving the corresponding products in moderate to good yields (up to 85%) with excellent enantioselectivities (up to 99% ee) under mild reaction conditions without extra additives.
Asymmetric epoxidation of 2-arylidene-1,3-diketones: Facile access to synthetically useful epoxides
Russo, Alessio,Lattanzi, Alessandra
experimental part, p. 2633 - 2638 (2010/07/16)
In this article the first enantioselective epoxidation reaction of acyclic and cyclic 2-arylidene-1,3-diketones is reported. Easily accessible or commercially available α,α-diaryl prolinols as the organocatalysts in the presence of tert-butyl hydroperoxid
