1308348-24-4Relevant academic research and scientific papers
Hydrogenolysis of N-protected aminooxetanes over palladium: An efficient method for a one-step ring opening and debenzylation reaction
Kovács, Ervin,Thurner, Angelika,Farkas, Ferenc,Faigl, Ferenc,Hegeds, László
, p. 32 - 36 (2011/05/17)
An efficient method for the palladium mediated hydrogenation of an optically active, N-protected aminooxetane derivative has been developed. Using appropriate solvents, in a one-step reaction, a chiral 1,4-aminoalcohol derivative [(2S,3R)-4-amino-3-benzoyloxy-2-benzylbutan-1-ol] was formed over a Pd/C catalyst, during hydrogenolytic ring opening and debenzylation reactions.
