1308381-98-7Relevant articles and documents
Total syntheses of 9-epoxyfalcarindiol and its diastereomer
Zhou, Yun,Huang, Yanli,Li, Shuoning,Yang, Pengfei,Zhong, Jiangchun,Yin, Jingwei,Ji, Kaijie,Yang, Yanqing,Ye, Ning,Wang, Lifeng,Wang, Mingan,Wang, Min,Bian, Qinghua
, p. 288 - 295 (2017/02/18)
The first total syntheses of 9-epoxyfalcarindiol 1a and its diastereomer 1b have been achieved. Central to our approach were the Zn-cyclopropane-based amino alcohol catalyzed enantioselective alkynylation of acrolein, the diastereoselective addition of a diynic ester to an epoxy aldehyde, and the asymmetric Sharpless epoxidation of allylic alcohol catalyzed with L-(+)-diethyl tartrate and Ti(OiPr)4.
Organocatalytic asymmetric epoxidation and tandem epoxidation/Passerini reaction under eco-friendly reaction conditions
Deobald, Anna Maria,Corrêa, Arlene G.,Rivera, Daniel G.,Paix?o, Márcio Weber
supporting information, p. 7681 - 7684 (2013/04/24)
An eco-friendly synthesis of highly functionalized epoxides and their incorporation into an organocatalytic multicomponent approach are reported. For this, a modified class of diarylprolinol silyl ethers was designed to enable high catalytic activity in an environmentally benign solvent system. The one-pot procedure showed great efficiency in promoting stereoselective multicomponent transformations in a tandem, 'green' fashion. Because of its non-residual, efficient and selective character, this synthetic design shows promise for large-scale applications in both diversity and target-oriented syntheses. The Royal Society of Chemistry 2012.
