130855-57-1Relevant articles and documents
A new approach to the efficient method for the asymmetric synthesis of (S)-O-, M-, P-fluorophenylalanines and their 2-methyl-substituted analogs
Saghiyan, Ashot S.,Petrosyan, Satenik G.,Manasyan, Luiza L.,Dadayan, Slavik A.,Geolchanyan, Arpine V.,Panosyan, Henry A.,Maleev, Victor I.,Khrustalev, Victor N.
scheme or table, p. 493 - 506 (2011/04/16)
The reactions of asymmetric C-alkylation of glycine and alanine in NiII complexes of their Schiff's bases with modified chiral auxiliaries (S)-2-N-[(N0-2-chlorobenzylprolyl)- amino]benzophenone and (S)-2-N-[N′-(3, 4-dimethylbenzylprolyl)amino]benzophenone by fluorine-substituted benzyl halogenides have been studied. As a result, a highly stereoselective and relatively rapid method for the asymmetric synthesis of (S)-o-, m-, p-fluorophenylalanines and their 2-methyl substituted analogs has been developed.
Chiral salen-metal complexes as novel catalysts for asymmetric phase transfer alkylations
Belokon, Yuri N.,North, Michael,Kublitski, Vadim S.,Ikonnikov, Nikolai S.,Krasik, Pavel E.,Maleev, Viktor I.
, p. 6105 - 6108 (2007/10/03)
Chiral, salen-metal complexes have been tested as catalysts for the C- alkylation of aldimine Schiff's bases of alanine esters with alkyl bromides under phase-transfer conditions (solid sodium hydroxide, toluene, ambient temperature, 1-10% of the catalyst
ASYMMETRIC SYNTHESIS OF HETEROORGANIC ANALOGS OF NATURAL COMPOUNDS. 2. A CONVENIENT PREPARATIVE METHOD FOR THE SYNTHESIS OF ENANTIOMERICALLY PURE (S)-(-)-o-, m-, and p-FLUOROPHENYLALANINES AND THEIR 2-METHYL-SUBSTITUTED ANALOGS.
Soloshonok, V. A.,Belokon', Yu. N.,Kukhar', V. P.,Chernoglazova, N. I.,Saporovskaya, M. B.,et al.
, p. 1479 - 1485 (2007/10/02)
A convenient preparative method for the synthesis of the enantiomerically pure o-, m-, and p-fluorophenylalanines and their α-methyl-substituted analogs by means of the alkylation with the corresponding fluorine-containing benzyl chlorides of glycine and