1308652-67-6 Usage
Uses
Used in Organic Synthesis:
9-[2-(Diphenylphosphino)phenyl]-9H-carbazole, Min. 97% Ph PhenCar-Phos is used as a ligand in organic synthesis for its ability to facilitate transition metal-catalyzed reactions. Its unique structure enhances the reactivity and selectivity of these reactions, leading to the formation of complex organic molecules with high yields and purity.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 9-[2-(Diphenylphosphino)phenyl]-9H-carbazole, Min. 97% Ph PhenCar-Phos is utilized as a ligand for the development of new drugs and drug candidates. Its high purity and reactivity contribute to the synthesis of novel compounds with potential therapeutic applications, aiding researchers in the discovery of new medicines.
Used in Transition Metal-Catalyzed Reactions:
9-[2-(Diphenylphosphino)phenyl]-9H-carbazole, Min. 97% Ph PhenCar-Phos is employed as a ligand in various transition metal-catalyzed reactions, such as cross-coupling and C-H activation reactions. Its presence improves the efficiency and selectivity of these reactions, enabling the synthesis of a wide range of organic compounds with diverse structures and functionalities.
Used in the Development of New Chemical Reactions:
9-[2-(Diphenylphosphino)phenyl]-9H-carbazole, Min. 97% Ph PhenCar-Phos is used as a key component in the development of new chemical reactions. Its unique structure and reactivity allow chemists to explore new synthetic pathways and create innovative methods for the synthesis of complex organic molecules.
Used in Exploring Synthetic Pathways:
In the field of synthetic chemistry, 9-[2-(Diphenylphosphino)phenyl]-9H-carbazole, Min. 97% Ph PhenCar-Phos is utilized for exploring new synthetic pathways. Its high purity and reactivity make it an ideal candidate for investigating novel reaction mechanisms and developing more efficient and sustainable synthetic routes to target molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 1308652-67-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,0,8,6,5 and 2 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1308652-67:
(9*1)+(8*3)+(7*0)+(6*8)+(5*6)+(4*5)+(3*2)+(2*6)+(1*7)=156
156 % 10 = 6
So 1308652-67-6 is a valid CAS Registry Number.
1308652-67-6Relevant academic research and scientific papers
Facile Assembly of Carbazolyl-Derived Phosphine Ligands and Their Applications in Palladium-Catalyzed Sterically Hindered Arylation Processes
Leung, Man Pan,Choy, Pui Ying,Lai, Wing In,Gan, Kin Boon,Kwong, Fuk Yee
, p. 1602 - 1609 (2019/08/20)
Phosphine ligands embodying a carbazolyl motif have been found to be successful in many palladium-catalyzed biaryl syntheses and direct C-H bond arylation processes. Here, a practical scaled-up synthesis of a series of carbazolyl-derived phosphine ligands, the PhenCarPhos series, is described. The original protocol for accessing the target ligand skeleton via aromatic C-N bond formation is limited by the use of a substoichiometric amount of copper salt and diamine catalysts, which both add cost and generate purification problems (significant amounts of side products and copper residues). In order to develop a more attractive and scalable synthetic pathway, a simple nucleophilic substitution method was attempted involving simple heating of 1-bromo-2-fluorobenzene, a carbazole derivative, and KOH in DMF without inert atmosphere protection. This route enables the large-scale synthesis of the desired ligand skeletons and minimizes the association of inseparable reduction side products. Particular examples of the use of these ligands in Pd-catalyzed sterically hindered arylation processes are also shown.
Highly efficient carbazolyl-derived phosphine ligands: Application to sterically hindered biaryl couplings
Chun To, Sheung,Yee Kwong, Fuk
, p. 5079 - 5081 (2011/06/10)
A new family of phosphine ligands bearing a bulky carbazolyl scaffold is described. With the combination of ligand 2a and Pd(OAc)2, difficult tri-ortho-substituted biaryl couplings are accomplished smoothly. In particular, the catalyst loading as low as 0.02 mol% of Pd for non-activated 2,6-disubstituted aryl chloride coupling can be achieved.
