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6-(3-chlorophenyl)-6,6a-dihydroisoindolo[2,1-a]quinazoline-5,11-dione is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

1308660-45-8

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1308660-45-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1308660-45-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,0,8,6,6 and 0 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1308660-45:
(9*1)+(8*3)+(7*0)+(6*8)+(5*6)+(4*6)+(3*0)+(2*4)+(1*5)=148
148 % 10 = 8
So 1308660-45-8 is a valid CAS Registry Number.

1308660-45-8Downstream Products

1308660-45-8Relevant academic research and scientific papers

A new three-component reaction: Green synthesis of novel isoindolo[2,1-a]quinazoline derivatives as potent inhibitors of TNF-α

Kumar, K. Siva,Kumar, P. Mahesh,Kumar, K. Anil,Sreenivasulu,Jafar, Ahamed A.,Rambabu,Krishna, G. Rama,Reddy, C. Malla,Kapavarapu, Ravikumar,Shivakumar,Priya, K. Krishna,Parsa, Kishore V. L.,Pal, Manojit

, p. 5010 - 5012 (2011)

Concurrent construction of five and six membered fused N-heretocyclic ring was achieved via a conceptually new three-component reaction affording 6,6a-dihydroisoindolo[2,1-a]quinazoline-5,11-diones as novel inhibitors of TNF-α in vitro. This represents one of the few examples of direct TNF-α inhibition by small molecules.

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