1308671-32-0Relevant academic research and scientific papers
One-pot construction of spirooxindole backbone via biocatalytic domino reaction
Liang, Yi-Ru,Hu, Yu-Jing,Zhou, Xue-Han,Wu, Qi,Lin, Xian-Fu
, p. 2923 - 2926 (2017)
A simple and environmentally friendly method to synthesize spiropyrazolo[3,4-b]pyridines derivatives starting from isatin, cyclic-1,3-diketone and 3-methyl-5-aminopyrazole was developed. With the optimized conditions for enzymes, solvents, enzyme loading and reaction time in hand, 9 compounds were obtained in acceptable yields. Moreover, the investigation in fluorescent properties of these products showed their potential application in the field of new fluorescent material.
New four-component reactions in water: A convergent approach to the metal-free synthesis of spiro[indoline/acenaphthylene-3,4′-pyrazolo[3,4-b] pyridine derivatives
Balamurugan, Kamaraj,Perumal, Subbu,Menéndez, J. Carlos
supporting information; experimental part, p. 3201 - 3208 (2011/05/30)
New four-component domino reactions are described that allow the one-pot synthesis of spiro[indoline/acenaphthylene-3,4′-pyrazolo[3,4-b]pyridine derivatives from the reaction of phenylhydrazine, 3-aminocrotononitrile, isatin/acenaphthylene-1,2-dione, and
