130888-73-2Relevant academic research and scientific papers
A regioselective route to 5-substituted isoxazole- And Isoxazoline- 3-phosphonates
Conti, Paola,Pinto, Andrea,Tamborini, Lucia,Dunkel, Petra,Gambaro, Veniero,Visconti, Giacomo L.,De Micheli, Carlo
experimental part, p. 591 - 596 (2009/07/10)
5-Substituted 3-(diethoxyphosphoryl)isoxazoles and -2- isoxazolines were synthesized regioselectively by 1,3-dipolar cy- cloaddition of (diethoxyphosphoryl)formonitrile oxide to monosub- stituted alkynes and alkenes. By applying this methodology to an N-
1,3-Dipolar Cycloaddition of Diethyl Nitromethylphosphonate, via the Nitrile Oxide, to Alkenes and 1-Alkynes. A Convenient One-Pot Synthesis of 3-Diethoxyphosphoryl-4,5-dihydroisoxazoles and 3-Diethoxyphosphorylisoxazoles
Zhang, Rongyu,Chen, Jian
, p. 817 - 819 (2007/10/02)
The one-pot reaction of diethyl nitromethylphosphonate with alkenes or 1-alkynes in the presence of phosphoryl chloride and triethylamine leads to 3-diethoxyphosphoryl-substituted 4,5-dihydroisoxazoles or isoxazoles, respectively, in good yields.
