1308917-78-3

Basic information

• Product Name: C₂₉H₃₇N₅O₄Si
• Synonyms: C₂₉H₃₇N₅O₄Si
• CAS NO: 1308917-78-3
• Molecular Weight: 547.729
• Mol File: 1308917-78-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₉H₃₇N₅O₄Si(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₉H₃₇N₅O₄Si(1308917-78-3)
• EPA Substance Registry System: C₂₉H₃₇N₅O₄Si(1308917-78-3)

Safety Data

• Hazardous Substances Data: 1308917-78-3(Hazardous Substances Data)

Upstream product

• 1092523-22-2 6-chloro-2-(ethylamino)pyridine-3-carbonyl fluoride 
• 1092523-21-1 6-chloro-2-(ethylamino)pyridine-3-carboxylic acid 
• 859169-20-3 1-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-acetic acid ethyl ester 
• 1308917-74-9 2-amino-7-chloro-1-ethyl-3-[1-(2-trimethylsilanyl-ethoxymethyl)-1H-imidazol-2-yl]-1H-[1,8]naphthyridin-4-one 
• 626604-89-5 [1-(2-trimethylsilanyl-ethoxymethyl)-1H-imidazol-2-yl]-acetonitrile 
• 38496-18-3 2,6-dichloropyridine-3-carboxylic acid 
• 15250-46-1 ethyl (4-iodophenyl)acetate 
• 101226-42-0 1-(2-trimethylsilanyl-ethoxymethyl)-1H-imidazole-2-carbaldehyde 

Downstream Products

• 1308917-77-2 (4-{7-Amino-8-ethyl-5-oxo-6-[1-(2-trimethylsilanyl-ethoxymethyl)-1H-imidazol-2-yl]-5,8-dihydro-[1,8]naphthyridin-2-yl}-phenyl)-acetic acid 
• 1308917-80-7 2-{4-[7-amino-8-ethyl-5-oxo-6-(1-{[2-(trimethylsilyl)ethoxy]methyl}-1H-imidazol-2-yl)-5,8-dihydro-1,8-naphthyridin-2-yl]phenyl}-N-[(4-cyclopropylmorpholin-3-yl)methyl]acetamide 

Relevant articles and documents

PYRIDINO-PYRIDINONE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF

The present invention relates to derivatives of pyridino-pyridinones, and to their preparation and use thereof, having activity as inhibitors of kinase activity of receptors for PDGF (platelet derived growth factors) ligands and optionally of receptors for the FLT3 (fms-like tyrosine kinase receptor) ligand receptors, said derivatives comprising compounds of formula (I): wherein the various substituent groups are more specifically defined herein. The compounds are suitable as therapeutics for the treatment of various proliferative diseases.