13093-87-3 Usage
Description
5-Benzyl-2,2-dimethyl-2,3,7,7a-tetrahydroimidazo[5,1-b][1,3]thiazole-3,7-dicarboxylic acid is a complex heterocyclic chemical compound characterized by the presence of a benzyl group, two methyl groups, and a tetrahydroimidazo[5,1-b][1,3]thiazole ring system. This molecule also features two carboxylic acid groups, which may contribute to its potential binding affinity to proteins or other biological targets. Its unique structure suggests it could possess specific biological activities, making it a promising candidate for pharmaceutical research and drug development.
Uses
Used in Pharmaceutical Development:
5-Benzyl-2,2-dimethyl-2,3,7,7a-tetrahydroimidazo[5,1-b][1,3]thiazole-3,7-dicarboxylic acid is utilized as a key intermediate in the synthesis of new pharmaceutical compounds. Its unique molecular structure, including the heterocyclic ring and carboxylic acid groups, provides a foundation for the development of drugs targeting various medical conditions.
Used in Drug Design and Optimization:
In the field of medicinal chemistry, 5-benzyl-2,2-dimethyl-2,3,7,7a-tetrahydroimidazo[5,1-b][1,3]thiazole-3,7-dicarboxylic acid serves as a building block for designing novel drug candidates. Its structural features can be modified to optimize pharmacokinetic properties, such as solubility, stability, and bioavailability, as well as to enhance the compound's interaction with specific biological targets.
Used in Biological Research:
5-Benzyl-2,2-dimethyl-2,3,7,7a-tetrahydroimidazo[5,1-b][1,3]thiazole-3,7-dicarboxylic acid is employed in biological research to study its interactions with proteins and other biomolecules. Understanding these interactions can provide insights into the compound's potential therapeutic effects and mechanisms of action, guiding further development and application in medicine.
Further research is necessary to fully explore the properties and potential applications of 5-benzyl-2,2-dimethyl-2,3,7,7a-tetrahydroimidazo[5,1-b][1,3]thiazole-3,7-dicarboxylic acid, including its role in drug discovery and its interactions with biological systems.
Check Digit Verification of cas no
The CAS Registry Mumber 13093-87-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,0,9 and 3 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 13093-87:
(7*1)+(6*3)+(5*0)+(4*9)+(3*3)+(2*8)+(1*7)=93
93 % 10 = 3
So 13093-87-3 is a valid CAS Registry Number.
13093-87-3Relevant articles and documents
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Holley et al.
, p. 136 (1948)
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The Chemical Reactivity of Penicillins and Other β-Lactam Antibiotics
Proctor, Philip,Gensmantel, Nigel P.,Page, Michael I.
, p. 1185 - 1192 (2007/10/02)
The rates of the acid catalysed hydrolysis of penicillins and cephalosporins are linear in Ho and, unlike other amides, show no rate maximum with increasing acidity.Electron-withdrawing substituents at C-6 in penicillins decrease the rate of hydrolysis with a ρI of ca. 4 and they decrease the rate when attached to the amine leaving group.The acylamido-group at C-6 in penicillins, but not at C-7 in cephalosporins, exhibits neighbouring group participation with a rate enhancement of ca. 103.The absence of penicillenic acid formation from benzylpenicillin in acidic solution is not due to the ionisation of the carboxy-group.These observations are rationalised by a scheme involving N-protonation and formation of an acylium ion intermediate.The alkaline hydrolysis of penicillins proceeds 102 faster than a β-lactam after correction for substituent effects.There is no evidence for substantial inhibition of amide resonance in the bicyclic β-lactam antibiotics, little evidence to indicate extra strain in these systems and no evidence that expulsion of the leaving group at C-3 in cephalosporins occurs in the transition state.
