130954-48-2

Upstream product

• 108-94-1 cyclohexanone 
• 66-77-3 1-naphthaldehyde 

Downstream Products

• 122214-17-9 1-[2-Methylene-cyclohex-(E)-ylidenemethyl]-naphthalene 

Relevant academic research and scientific papers

Ruthenium-catalysed synthesis of chiral exocyclic allylic alcoholsviachemoselective transfer hydrogenation of 2-arylidene cycloalkanones

An exclusive asymmetric reduction of C=O bonds of 2-arylidene four-, five-, six-, and seven-membered cycloalkanones has been studied systematically. The asymmetric transfer hydrogenation was performed using a robust and commercially available chiral diamine-derived ruthenium complex as a catalyst and HCOOH/Et3N as a hydrogen source under mild conditions, giving 51 examples of chiral exocyclic allylic alcohols in up to 96% yield and 99% ee. This method was also applicable to the gram-scale synthesis of the active intermediates of the anti-inflammatory loxoprofen and natural product (?)-goniomitine.

Novel racemic chiral organic boron nitrogen fluorescent compound and preparation method thereof (by machine translation)

The novel chiral organic boron nitride fluorescent compound, is characterized in that, takes a cheap,readily available monoiodobenzene derivative, carboxylic acid derivative as a raw material, to react at a certain temperature with a common organic solvent as a reaction solvent, for a certain time, high yield, to selectively obtain a novel chiral organic boron nitrogen fluorescent compound . The catalyst, can be recovered, at a certain temperature for a certain period of time for a certain period of time to produce a novel chiral organic boron-nitrogen fluorescent compound with low cost,and a high yield, and selectivity, can be, obtained at a certain temperature for a certain period, of time with a certain period of time and high yield. (by machine translation)

Highly Enantioselective Hydrogenation of α-Arylmethylene Cycloalkanones Catalyzed by Iridium Complexes of Chiral Spiro Aminophosphine Ligands

The highly efficient asymmetric hydrogenation of α-arylmethylene cycloalkanones catalyzed by Ir-complexes of chiral spiro aminophosphine ligands was developed, providing chiral exo-cyclic allylic alcohols at high yields with excellent enantioselectivities (up to 97% ee) and high turnover numbers (S/C up to 10,000). This new reaction provided an efficient method for the synthesis of the key intermediate of the active form of the anti-inflammatory loxoprofen.

Direct preparation of monoarylidene derivatives of aldehydes and enolizable ketones with DIMCARB

(Matrix presented) Aryl α,β-unsaturated ketones and aldehydes were synthesized, in moderate to excellent yields, with use of dimethylammonium dimethyl carbamate (DIMCARB) as a recyclable reaction medium and as a catalyst.