1309654-00-9Relevant academic research and scientific papers
Synthesis and pharmacological evaluation of N-(6-chlorobenzo[d]thiazol-2- yl)hydrazine carboxamide derivatives of benzothiazole
Gilani, Sadaf J.,Khan, Suroor A.
, p. 3316 - 3328 (2013/07/19)
A series of 6-substituted-1,2,4-triazolo-[3,4-b]-1,3,4-thiadiazole (6a-g) and 1,3,4-oxadiazole (7a-g, 8) derivatives of benzothiazole were synthesized in satisfactory yield and pharmacologically evaluated for their anti-inflammatory, analgesic, ulcerogenic, and lipid peroxidation activities by known experimental models. All the synthesized compounds were in good agreement with elemental and spectral data. Some of the synthesized compounds have significant anti-inflammatory and analgesic activities. Ulcerogenic and irritative action on the gastrointestinal mucosa, in comparison with standard are low.
