1309660-35-2Relevant academic research and scientific papers
Copper catalyzed decarboxylative alkynylation of quaternary α-cyano acetate salts
Feng, Yi-Si,Xu, Zhong-Qiu,Mao, Long,Zhang, Feng-Feng,Xu, Hua-Jian
supporting information, p. 1472 - 1475 (2013/06/27)
Cu-catalyzed decarboxylative alkynylation of quaternary α-cyano acetate salts with alkynyl bromides and alkynyl chlorides is described. This new reaction can be used for preparing functionalized butynenitrile derivatives.
Synthesis of α-Aryl nitriles through palladium-catalyzed decarboxylative coupling of cyanoacetate salts with aryl halides and triflates
Shang, Rui,Ji, Dong-Sheng,Chu, Ling,Fu, Yao,Liu, Lei
supporting information; experimental part, p. 4470 - 4474 (2011/06/24)
Worth its salt: The palladium-catalyzed decarboxylative coupling of the cyanoacetate salt as well as its mono- and disubstituted derivatives with aryl chlorides, bromides, and triflates is described (see scheme). This reaction is potentially useful for the preparation of a diverse array of α-aryl nitriles and has good functional group tolerance. S-Phos=2-(2,6- dimethoxybiphenyl)dicyclohexylphosphine), Xant-Phos=4,5-bis(diphenylphosphino)- 9,9-dimethylxanthene. Copyright
