1309767-73-4Relevant academic research and scientific papers
Selective formation of 1,5-substituted sulfonyl triazoles using acetylides and sulfonyl azides
Meza-Avina, Maria Elena,Patel, Mudita Kishor,Lee, Cylivia B.,Dietz, Thomas J.,Croatt, Mitchell P.
, p. 2984 - 2987 (2011)
The reaction of acetylides with sulfonyl azides was found to selectively form 1,5-substituted sulfonyl triazoles. This reaction thus provides access to the regioisomeric product as compared to the popular copper-catalyzed azide-alkyne cycloaddition. The reaction is efficient and selective with a variety of alkyne sources and sulfonyl azides and can incorporate an additional electrophile to yield 1,4,5-trisubstituted sulfonyl triazoles.
