1309781-71-2Relevant academic research and scientific papers
Palladium-catalyzed cascade reaction for the synthesis of substituted isoindolines
Williams, Florence J.,Jarvo, Elizabeth R.
, p. 4459 - 4462 (2011/06/26)
Arylate then cyclize: A palladium(II)-catalyzed cascade sequence has been developed to provide highly diastereomerically enriched cis-1-aryl-3-vinyl isoindolines (see scheme). The method uses commercially available aryl boronic acids and boroxine compounds containing a variety of electron-rich, -neutral, or -poor aromatic groups. Ts=4-toluenesulfonyl. Copyright
