1309944-49-7

Upstream product

• 118-48-9 isatoic anhydride 
• 83-38-5 2,6-dichlorobenzaldehyde 
• 62-53-3 aniline 

Relevant academic research and scientific papers

Hydroxyapatite nanoparticles (HAP NPs): A green and efficient heterogeneous catalyst for three-component one-pot synthesis of 2,3-dihydroquinazolin-4(1H)-one derivatives in aqueous media

Hydroxyapatite nanoparticles (HAP NPs) are found to be an efficient catalyst for synthesis of 2,3-dihydroquinazolin-4(1H)-one derivatives in aqueous media via a three-component one-pot condensation of isatoic anhydride and aromatic aldehydes with primary amines or ammonium salts. The nanocatalyst (characterized by FT-IR, XRD, SEM-EDS and TEM techniques) is easily recyclable six times without the significant loss of catalytic activity. Other remarkable features include the wide range of functional group tolerance and good to excellent yields of the products under mild reaction conditions.

Dihydroquinazolin-4(1H)-one derivatives as novel and potential leads for diabetic management

A variety of dihydroquinazolin-4(1H)-one derivatives (1–37) were synthesized via “one-pot” three-component reaction scheme by treating aniline and different aromatic aldehydes with isatoic anhydride in the presence of acetic acid. Chemical structures of c

Green and catalyst-free one-pot synthesis of 2,3-dihydroquinazolin-4(1H)-ones in water

A facile and highly efficient protocol was successfully applied to synthesize mono- and disubstituted dihydroquinazolinones through a three-component coupling reaction of isatoic anhydride, aniline or ammonium acetate, and aromatic aldehydes in refluxing

Acetic acid-promoted, efficient, one-pot synthesis of 2,3- dihydroquinazolin-4(1H)-ones

A simple, efficient, and general method has been developed for one-pot, three-component synthesis of 2,3-dihydroquinazolin-4(1H)-one derivatives based on a condensation reaction strategy of isatoic anhydride, aldehydes, and amines using acetic acid under reflux conditions.