131001-90-6

Basic information

• Product Name: Benzoic acid, 2-ethenyl-4-methyl-, methyl ester
• CAS NO: 131001-90-6
• Molecular Formula: C11H12O2
• Molecular Weight: 176.215
• Mol File: 131001-90-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 2-ethenyl-4-methyl-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 2-ethenyl-4-methyl-, methyl ester(131001-90-6)
• EPA Substance Registry System: Benzoic acid, 2-ethenyl-4-methyl-, methyl ester(131001-90-6)

Safety Data

• Hazardous Substances Data: 131001-90-6(Hazardous Substances Data)

Upstream product

• 75927-49-0 pinacol vinylboronate 
• 191104-16-2 2-(trifluoromethanesulfonyloxy)4-methylbenzoic acid methyl ester 
• 50-85-1 2-hydroxy-p-toluic acid 
• 4670-56-8 methyl 2-hydroxy-4-methylbenzoate 
• 7697-27-0 2-bromo-4-methylbenzoic acid 
• 87808-49-9 2-bromo-4-methyl-benzoic acid methyl ester 

Downstream Products

• 1399181-55-5 methyl 2-ethyl-4-methylbenzoate 
• 131001-95-1 2-<(2-methoxycarbonyl-5-methylphenyl)methyl>-1,3-dioxane 

Relevant articles and documents

Rhodium(III)-Catalyzed Oxidative Intramolecular 1,1-Oxyamination of Alkenes with Protected Amino Acids to Produce Oxazoloisoindole-2,5-diones

It has been established that an electron-deficient bis(ethoxycarbonyl)-substituted cyclopentadienyl (CpE) rhodium(III) complex catalyzes the oxidative intramolecular 1,1-oxyamination of alkenes with N-benzoyl amino acids to produce oxazoloisoindole-2,5-diones. Experimental and theoretical mechanistic studies revealed that this oxidative 1,1-oxyamination proceeds via not the aza-Wacker reaction but the formation of a rhoda(III)oxazolidine initiated by the carboxylic acid-directed N?H bond cleavage.

HISTONE DEMETHYLASE INHIBITORS

Provided herein are substituted pyrazolylpyridine, pyrazolylpyridazine, and pyrazolylpyrimidine derivative compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for inhibition histone demethylase. Furthermore, the subject compounds and compositions are useful for the treatment of cancer, such as prostate cancer, breast cancer, bladder cancer, lung cancer and/or melanoma and the like.