1310089-92-9

Upstream product

• 90-02-8 salicylaldehyde 
• 249290-19-5 N-(1,2,3,4-tetrahydroacridin-9-yl)octane-1,8-diamine 
• 118-92-3 anthranilic acid 
• 108-94-1 cyclohexanone 
• 5396-30-5 9-chloro-1,2,3,4-tetrahydroacridine 
• 96447-10-8 spiro<2H-3,1-benzoxazine-2,1'-cyclohexan>-4(1H)-one 

Relevant academic research and scientific papers

O-Hydroxyl- or o-amino benzylamine-tacrine hybrids: Multifunctional biometals chelators, antioxidants, and inhibitors of cholinesterase activity and amyloid-β aggregation

In an effort to identify novel multifunctional drug candidates for the treatment of Alzheimer's disease (AD), a series of hybrid molecules were synthesised by reacting N-(aminoalkyl)tacrine with salicylic aldehyde or derivatives of 2-aminobenzaldehyde. Th

Synthesis and evaluation of heterobivalent tacrine derivatives as potential multi-functional anti-Alzheimer agents

A new series of heterobivalent tacrine derivatives were designed, synthesized and evaluated as potential multi-functional anti-Alzheimer agents for their inhibitory activity on cholinesterases, antioxidant activity and self-induced β-amyloid (Aβ) aggregat