13103-58-7

Basic information

• Product Name: Acetamide, N-[4-[(4-chlorophenyl)methoxy]phenyl]-
• CAS NO: 13103-58-7
• Molecular Formula: C15H14ClNO2
• Molecular Weight: 275.735
• Mol File: 13103-58-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Acetamide, N-[4-[(4-chlorophenyl)methoxy]phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Acetamide, N-[4-[(4-chlorophenyl)methoxy]phenyl]-(13103-58-7)
• EPA Substance Registry System: Acetamide, N-[4-[(4-chlorophenyl)methoxy]phenyl]-(13103-58-7)

Safety Data

• Hazardous Substances Data: 13103-58-7(Hazardous Substances Data)

Upstream product

• 103-90-2 4-acetaminophenol 
• 622-95-7 4-chlorobenzyl bromide 
• 104-83-6 1-Chloro-4-(chloromethyl)benzene 

Downstream Products

• 1277185-35-9 C₂₁H₁₇ClN₄O₃ 
• 1277185-40-6 C₂₁H₁₆ClN₃O₅ 
• 1277185-44-0 C₂₂H₁₆ClN₃O₅ 
• 34762-56-6 4-(4-chlorobenzoxy)phenyl amine 

Relevant articles and documents

Synthesis and biological evaluation of pentanedioic acid derivatives as farnesyltransferase inhibitors

Structure-based virtual screening of a commercial library identified pentanedioic acid derivatives (6 and 13b) as a kind of novel scaffold farnesyltransferase inhibitors (FTIs). Chemical modifications of the lead compounds, biological assays and analysis of the structure-activity relationships (SAR) were conducted to discover more potent FTIs. Some of them displayed excellent inhibition against FTase, and among them, the most active compound 13n with an IC50 value of 0.0029 μM and SAR analysis might be helpful to the discovery of more potent FTIs. This journal is