131035-58-0Relevant academic research and scientific papers
SEMI-SYNTHESIS OF A.23187 (CALCIMYCIN) ANALOGS WITH 5-N-AMINO SUBSTITUENTS. THEIR COMPLEXATION OF CALCIUM AND MAGNESIUM
Samih, Fouzia,Prudhomme, Michelle,Dauphin, Gerard,Jeminet, Georges
, p. 5177 - 5186 (2007/10/02)
The semi-synthesis of A.23187 (calcimycin) analogs 1-4 bearing the respective substituents: 5-NH2, 5-NHCH3, 5-N(CH3)2, 5-NHCOCH3 was carried out.The complexing properties of 1-4 for calcium and magnesium were determined by two-phase experiments (water/toluene-butanol 70:30 W:W) and found to be much weaker than these of A.23187 or X.14885A.There was a discrepancy with theoretical predictions made from model carboxybenzoxazoles.
