1310487-84-3Relevant academic research and scientific papers
Acylpyrazolones possessing a heterocyclic moiety in the acyl fragment: Intramolecular: vs. intermolecular zwitterionic structures
Kurteva, Vanya B.,Nikolova, Rositsa P.,Petkova, Zhanina S.,Rusew, Rusi I.,Shivachev, Boris L.,Todorova, Stanislava E.
, p. 1080 - 1086 (2022/02/07)
A series of acylpyrazolones possessing a methylene bridged heterocyclic unit in the acyl fragment are synthesized and characterized in solution and the solid state. It is found that the products exist in the solid state as intramolecular or intermolecular zwitterions between the tautomeric pyrazolone hydroxyl group and the nitrogen atom of the acyl substituents. Aliphatic amine units with a variable number and type of heteroatoms and ring size are attached and the type of zwitterions formed are analysed by single crystal XRD. It is observed that the products coordinate spontaneously with cesium carbonate being used as a base. These complexes are also studied by XRD.
Synthesis and antimicrobial activity of some new 4-hetarylpyrazole and furo[2,3-c]pyrazole derivatives
Bondock, Samir,Khalifa, Wesam,Fadda, Ahmed A.
experimental part, p. 2555 - 2561 (2011/06/21)
In continuation of our efforts to find a new class of antimicrobial agents, a series of 4-hetarylpyrazoles and furo[2,3-c]pyrazoles were prepared via the reaction of 2-chloro-1-(5-hydroxy-3-methyl-1-phenyl-1H-pyrazol-4-yl)ethanone (1) with an appropriate
