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19735-89-8

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19735-89-8 Usage

Description

1,2-Dihydro-5-methyl-2-phenyl-3H-pyrazol-3-one is a heterocyclic chemical compound belonging to the class of pyrazolines, which are derivatives of azines. It is characterized by its unique ring structure that includes carbon, hydrogen, nitrogen, and one oxygen atom. 1,2-Dihydro-5-methyl-2-phenyl-3H-pyrazol-3-one's properties can be influenced by the position and type of functional groups attached to it, making it a versatile molecule for various applications.

Uses

Used in Chemical Research:
1,2-Dihydro-5-methyl-2-phenyl-3H-pyrazol-3-one is used as a research compound for studying its chemical properties and potential applications in various fields. Its heterocyclic structure and the possibility of functional group modifications make it an interesting subject for scientific investigation.
Used as a Potential Bioactive Agent:
Due to its unique structure and properties, 1,2-Dihydro-5-methyl-2-phenyl-3H-pyrazol-3-one is considered a potential bioactive agent. It may have applications in the development of new drugs or therapeutic agents, given its ability to interact with biological systems. Further research is needed to explore its potential in this area and to understand its mechanism of action.

Check Digit Verification of cas no

The CAS Registry Mumber 19735-89-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,7,3 and 5 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 19735-89:
(7*1)+(6*9)+(5*7)+(4*3)+(3*5)+(2*8)+(1*9)=148
148 % 10 = 8
So 19735-89-8 is a valid CAS Registry Number.
InChI:InChI=1/C10H10N2O/c1-8-7-10(13)12(11-8)9-5-3-2-4-6-9/h2-7,11H,1H3

19735-89-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-Methyl-2-phenyl-1,2-dihydropyrazol-3-one

1.2 Other means of identification

Product number -
Other names 1-Phenyl-3-methylpyrazol-5-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:19735-89-8 SDS

19735-89-8Relevant articles and documents

RECYCLIZATION OF 4-METHYL(PHENYL)-2,3-DIHYDRO-1H-1,5-BENZODIAZEPIN-2-ONES

Gaponov, A. A.,Solomko, Z. F.,Bozhanova, N. Ya.,Pantyukh, E. I.

, p. 836 (1989)

Depending on the reaction conditions, the hydrazinolysis of 4-(acetyl-methylene)-1,2,3,5-tetrahydro-1,5-benzodiazepin-2-one affords N-(2-aminophenyl)-5-methyl-3-pyrazolylacetamide or 2-benzimidazo-5-methyl-3-pyrazolylmethane.In the presence of phenylhydrazine, 3,4,5-trimethyl-1,5-benzodiazepine is recyclized to 3,4,5-trimethyl-1-phenyl-2-pyrazole.

Design and Synthesis of Fused and Spiro Pyrazole Derivatives

Abdelrahman, E. F.,Assy, M. G.,Shehta, W.

, p. 1245 - 1250 (2020)

Abstract: Condensation of 5-methyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one with p-hydroxybenzaldehyde in alcoholic sodium hydroxide yielded (Z)-4-(4-hydroxybenzylidene)-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one which was treated with acetylacetone, hydrazine hydrate, ethyl cyanoacetate, and ethyl acetoacetate to afford pyranopyrazole, pyrazolopyrazole, pyrazolopyridine, and 6-aminopyrazolopyridine derivatives, respectively. 5-Methyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one was also reacted at the enamino carbon atom with 2,4-dichlorobenzoyl isothiocyanate, thiosemicarbazide, and hydrazine hydrate to produce pyrazolooxazine, pyrazolopyrazole, and spiro[pyrazole-3,3′-pyrazolo[3,4-c]pyrazole] derivatives.

Synthesis of Pyrano, Pyrido, Oxazino, and Spiro Pyrazole Derivatives and Their Antimicrobial Activity

Abdelrahman, E. F.,Assy, M. G. M.,Farhan, M. E.,Shehta, W.

, p. 1832 - 1839 (2020)

Abstract: Condensation of 5-methyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one with 4-hydroxybenzaldhyde in alcoholic sodium hydroxide yielded 4-(4-hydroxybenzylidene)-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one, and treatment of the latter with acetylacetone, hydrazine hydrate, ethyl cyanoacetate, and ethyl acetoacetate gave pyranopyrazole, pyrazolopyrazole, and pyrazolopyridine derivatives. 5-Methyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one was reacted with 2,4-dichlorobenzoyl isothiocyanate, thiosemicarbazide, and hydrazine hydrate to afford pyrazolooxazine, pyrazolopyrazole, and spiro[pyrazole-3,3′-pyrazolo[3,4-c]pyrazole] derivatives. Some of the newly synthesized compounds showed high antimicrobial activity against three microbial strains (S. aureus, E. coli, C. albicans).

Efficient Synthesis of Five Types of Heterocyclic Compounds via Intramolecular Elimination Using Ultrasound-Static Heating Technique

Jiang, Hongfei,Dong, Xueyang,Jin, Xin,Zhu, Danyang,Yin, Ruijuan,Yu, Rilei,Wan, Shengbiao,Zhang, Lijuan,Jiang, Tao

supporting information, p. 2009 - 2013 (2018/07/31)

An experimental technique, ultrasound-static heating, has been developed for the efficient synthesis of heterocyclic compounds. The technique involves ultrasonic irradiation and static heating processes. First, the ultrasonic irradiation process is performed to form an intermediate of the heterocyclic compound under mild conditions and the subsequent static heating process (heating the intermediate under solvent-free conditions without stirring) produces the target heterocyclic compounds via intramolecular elimination.

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