1310492-83-1

Basic information

• Product Name: 2-(4-chlorophenyl)-7-methyl-3-(phenylthio)-imidazo[1,2-a]pyridine
• Synonyms: 2-(4-chlorophenyl)-7-methyl-3-(phenylthio)-imidazo[1,2-a]pyridine
• CAS NO: 1310492-83-1
• Molecular Weight: 350.871
• Mol File: 1310492-83-1.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2-(4-chlorophenyl)-7-methyl-3-(phenylthio)-imidazo[1,2-a]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-chlorophenyl)-7-methyl-3-(phenylthio)-imidazo[1,2-a]pyridine(1310492-83-1)
• EPA Substance Registry System: 2-(4-chlorophenyl)-7-methyl-3-(phenylthio)-imidazo[1,2-a]pyridine(1310492-83-1)

Safety Data

• Hazardous Substances Data: 1310492-83-1(Hazardous Substances Data)

Upstream product

• 65964-62-7 2-(4-chlorophenyl)-7-methyl-imidazo[1,2-a]pyridine 
• 80-17-1 benzenesufonyl hydrazide 
• 882-33-7 diphenyldisulfane 

Relevant articles and documents

NH4I-catalyzed chalcogen(S/Se)-functionalization of 5-membered N-heteroaryls under metal-free conditions

Herein, we described the NH4I-catalyzed C–H bond chalcogenation of N-heteroaryls in the presence of a minimum amount of DMSO/H2O/acetic acid as additives (2.5/2.5/1 M equiv., respectively), under metal-free conditions. Under optimized conditions, a wide variety of sulfenyl/selenyl imidazo[1,2-α]pyridines were prepared in very good yields. Moreover, the present approach was also highly efficient for the chalcogenation of different 5-membered N-heteroaryls, e.g., indole, imidazothiazole, indazole and imidazopyrimidine derivatives.

Preparing method for C-3 position sulfoimidazo[1,2-a] pyridine compound

The invention discloses a preparing method for a C-3 position sulfoimidazo[1,2-a] pyridine compound. The preparing method includes the step that an imidazo[1,2-a] pyridine compound and a sulfohydrazide compound serving as raw materials, tert-butyl hydroperoxide serving as an oxidizing agent, acetonitrile serving as solvent, and an iodine compound serving as a catalyst react at the reaction temperature of 60 DEG C-120 DEG C to obtain the C-3 position sulfoimidazo[1,2-a] pyridine compound. Compared with a traditional synthetic method, the preparing method has the advantages that reaction conditions are moderate, environment pollution is little, reaction smells are small, the yield is high, functional group compatibility is high, and separation and purification are convenient.

An efficient and clean CuI-catalyzed chalcogenylation of aromatic azaheterocycles with dichalcogenides

A highly efficient and environmentally friendly method for catalytic chalcogenylation of imidazopyridines, imidazopyrimidines, indoles, and pyrrolo[2,3-b]pyridines with dichalcogenides has been developed by using CuI as catalyst under air. The reactions proceed smoothly to give the desired products in moderate to excellent yields, without the presence of other additive.